Sökning: "Gene transfer"

Visar resultat 6 - 10 av 308 avhandlingar innehållade orden Gene transfer.

  1. 6. Targeted gene transfer in the developing central nervous system using viral vectors

    Författare :Simon Stott; Brain Repair and Imaging in Neural Systems (BRAINS); []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurology; neuropsychology; neurophysiology; Neurologi; Medicin människa och djur ; Medicine human and vertebrates ; gene transfer; in utero; neonatal; GDNF; nigrostriatal; dopamine; AAV; retrovirus; neuropsykologi; neurofysiologi;

    Sammanfattning : Dopamine (DA) is a neurotransmitter that plays a fundamental role in many aspects of normal brain function. The majority of DA neurons in the brain reside in one region ? the midbrain ? and project axonal connections to specific areas. One of the main target regions of the DA system is the striatum. LÄS MER

  2. 7. Using Trees to Capture Reticulate Evolution : Lateral Gene Transfers and Cancer Progression

    Författare :Ali Tofigh; Jens Lagergren; Mike Steel; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Lateral Gene Tranfer; Horizontal Gene Transfer; Cancer Progression; Bioinformatics; Bioinformatik; Computer science; Datalogi;

    Sammanfattning : The historic relationship of species and genes are traditionally depicted using trees. However, not all evolutionary histories are adequately captured by bifurcating processes and an increasing amount of research is devoted towards using networks or network-like structures to capture evolutionary history. LÄS MER

  3. 8. Development of lentiviral vectors for CNS gene transfer

    Författare :Johan Jakobsson; Brain Repair and Imaging in Neural Systems (BRAINS); []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicin människa och djur ; Medicine human and vertebrates ; Biotechnology; Gene Therapy; Neurological disorders;

    Sammanfattning : Gene therapy in the brain is a promising treatment strategy that in the future may be used for several brain disorders, including Parkinson's disease, Alzheimer's disease and lysosomal storage diseases. By introducing a new gene, rather than providing a classical pharmacological drug, gene therapy offers the opportunity to treat neurological disorders by a single intervention. LÄS MER

  4. 9. Horizontal gene transfer in plants - The story of PgiC2

    Författare :Pernilla Vallenback; Biologiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; plant genetics; Festuca ovina; PgiC; Horizontal gene transfer;

    Sammanfattning : Sheep's fescue, Festuca ovina, is a common grass found all over Eurasia. In populations in southern Sweden some individuals were found to have two copies of the gene for cytoplasmic phosphoglucose isomerase, PgiC. LÄS MER

  5. 10. Computational Problems in Modeling Evolution and Inferring Gene Families

    Författare :Mehmood Alam Khan; Lars Arvestad; Jens Lagergren; Christophe Dessimoz; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Evolution; Phylogenetics; Lateral Gene Transfer; Gene Families; Clustering; Datalogi; Computer Science;

    Sammanfattning : Over the last few decades, phylogenetics has emerged as a very promising field, facilitating a comparative framework to explain the genetic relationships among all the living organisms on earth. These genetic relationships are typically represented by a bifurcating phylogenetic tree — the tree of life. LÄS MER