Sökning: "Gene transfer"
Visar resultat 16 - 20 av 308 avhandlingar innehållade orden Gene transfer.
16. Nucleic acid in gene delivery and gene regulation
Sammanfattning : The concept of gene therapy, initially attributed to a technology that would allow the correction of inherited genetic disease, has evolved over the years. The realization of the immense technical hurdles to achieve genetic correction led to a broadening of the concept now including the transfer of genetic material whose expression will counteract, mitigate or revert a disease phenotype. LÄS MER
17. Plant lipid transfer proteins : Evolution, expression and function
Sammanfattning : The plant non-specific lipid transfer proteins (nsLTPs) are known for the ability to transfer different lipids in vitro, but their in vivo functions have not yet been elucidated. They seem to play a role in the defense against biotic and abiotic stresses; the gene expression of nsLTPs is often upregulated when exposed to stresses. LÄS MER
18. Regulation of gene expression in fruit flies : how does it start, and will it be remembered?
Sammanfattning : One of the most distinctive features of eukaryotic chromosomes is the bundling of DNA together with functionally associated RNA and proteins in chromatin. This allows huge amounts of DNA to be packed inside the very tiny space of the nucleus, and alterations in the structure of chromatin enable access to the DNA for transcription (“reading” genes by production of RNA copies). LÄS MER
19. Computational discovery of antibiotic resistance genes and their horizontal transfer
Sammanfattning : Antibiotic resistance is increasing among clinical infections and represents one of the most serious threats to public health. Pathogens often become resistant by acquiring mobile antibiotic resistance genes (ARGs) via horizontal gene transfer (HGT). LÄS MER
20. Advancing systems biology of yeast through machine learning and comparative genomics
Sammanfattning : Synthetic biology has played a pivotal role in accomplishing the production of high value commodities, pharmaceuticals, and bulk chemicals. Fueled by the breakthrough of synthetic biology and metabolic engineering, Saccharomyces cerevisiae and various other yeasts (such as Yarrowia lipolytica , Pichia pastoris ) have been proven to be promising microbial cell factories and are frequently used in scientific studies. LÄS MER