Sökning: "Gene Sharp"

Visar resultat 6 - 10 av 16 avhandlingar innehållade orden Gene Sharp.

  1. 6. Isoform-specific regulation of Drosophila gut immunity and regeneration by the POU/Oct transcription factor Nub/Pdm1

    Författare :Xiongzhuo Tang; Ylva Engström; Tony Ip; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; POU; Nubbin; Drosophila; intestinal stem cell; epithelium regeneration; midgut; mitosis; Antimicrobial peptides; innate immunity; NF-κB; bacterial infection; transcriptional regulation; homeostasis; Molecular Biology; molekylärbiologi;

    Sammanfattning : Innate immune reactions protect organisms against a variety of infections.  In metazoans, these reactions involve both cellular and humoral responses. The immune responses have to be well-tuned, as excessive immune activation is associated with tissue-specific pathologies. LÄS MER

  3. 7. Involvement of evolutionarily plastic regions in cancer associated CHR3 aberrations

    Författare :Eva Darai-Ramqvist; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : A functional test to identify tumor antagonizing regions on chromosome 3 (chr3), called the Elimination Test, was developed in our group. It is based on microcell mediated transfer of human chr3 into mouse or human tumor cells and analysis of the monochromosomal hybrids after their growth in vivo. LÄS MER

  4. 8. The Biology of Hematopoietic Stem Cells: transgenic approaches to Dissect Native and Perturbed Hematopoiesis

    Författare :Petter Säwén; Avdelningen för molekylär hematologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : Hematopoiesis is defined as the ongoing production of blood cells. As most mature blood cells are relatively short-lived and require continuous replacement, hematopoiesis is characterized by an extraordinary turnover rate with production of trillions of new blood cells every day. LÄS MER

  5. 9. Evolution of cellular complexity and other remarkable features in Gemmataceae : Complex bacterial lineages defy prokaryotic trends

    Författare :Mayank Mahajan; Siv G. E. Andersson; James O. McInerney; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Molecular evolution; Planctomycetes; Gemmataceae; functional organization; signalling; protein interaction; peptidoglycan; membranes; cell division; radiation tolerance; Pfam; SCOP; comparative genomics; protein architecture; domain shuffling and orthologous clustering; Bioinformatics; Bioinformatik; Biologi med inriktning mot molekylär evolution; Biology with specialization in Molecular Evolution; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi;

    Sammanfattning : Bacteria of the family Gemmataceae belong the phylum Planctomycetes and are remarkable because of their complex cellular architectures, previously considered to be traits exclusive to eukaryotes. This thesis provides clues to the atypical cell envelope, the enhanced radiotolerance and the amazing cellular complexity of these bacteria. LÄS MER

  7. 10. Evolutionary patterns and processes of bacteriophages, particularly P2-like phages

    Författare :Anders Nilsson; Siv Andersson; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Genetics; genetik;

    Sammanfattning : DNA sequencing of structural genes of temperate P2-like prophages from isolates of Escherichia coli bacteria showed that the difference between these genes was very small. Separate phylogenetic analyses on the genes resulted in unresolved trees, caused by a high level of homologous recombination, which implied that homologous recombination is the most important source of new genetic variation for P2-like phages infecting E. LÄS MER