Sökning: "Geert van Loo"
Hittade 1 avhandling innehållade orden Geert van Loo.
1. The role and mechanism of ubiquitin system in innate immune regulation
Sammanfattning : Pattern-recognition receptors (PRRs) include the cell surface or endosomal membrane localized Toll-like receptors (TLRs) and the cytoplasmic PRRs such as RIG-I-like receptors (RLRs), NOD-like receptors (NLRs) and cytoplasmic DNA receptors (CDRs). Triggering of PRRs culminates in the transcriptional induction of pro-inflammatory cytokines and type I interferons (IFNs) that coordinate protection against pathogens but require tight control to avert inflammatory diseases. LÄS MER
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