Sökning: "Gastrointestinal tumors"

Visar resultat 11 - 15 av 31 avhandlingar innehållade orden Gastrointestinal tumors.

  1. 11. Peptide Receptor Radionuclide Therapy in Neuroendocrine Neoplasms : Aspects of tumour characteristics, receptor recycling and peptide mass

    Författare :Ulrika Jahn; Anders Sundin; Mark Lubberink; Ulrike Garske-Román; Mona-Elisabeth Rootwelt-Revheim; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neuroendocrine tumors; Peptide receptor radionuclide therapy PRRT ; Peptide; Small-Intestinal; Pancreatic; Dosimetry; Somatostatin receptor;

    Sammanfattning : Neuroendocrine neoplasm (NEN) can arise in any part of the body, but most commonly in the lungs, bronchi, and the gastrointestinal tract including the pancreas. They combine neuroendocrine and tissue-of-origin-specific characteristics; explaining different symptoms depending on the organ of origin. LÄS MER

  3. 12. The oncogenic role of histone chaperone ASF1 proteins in solid tumors

    Författare :Yujiao Wu; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Chromatin is the essential medium connecting regulatory signals such as transcription factors and signaling pathways to the alteration of gene activity and cellular phenotypes. Aberrant chromatin (epigenetic) environment plays an important role in carcinogenesis. LÄS MER

  4. 13. Therapy of neuroendocrine tumors with 177Lu-octreotate - Human tumor cell types and models and optimization of treatment : Terapi av neuroendokrina tumörer med 177Lu-octreotate

    Författare :Johanna Dalmo; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; somatostatin; radionuclide therapy; receptor up-regulation; RBP; nephrotoxicity;

    Sammanfattning : Neuroendocrine (NE) tumors (NET) have often metastasized at the time of diagnose, which makes it hard to cure patients with NET. Radiolabeled hormone analogues (especially somatostatin analogues, SS) can be used for diagnostics (e.g. 111In-octreotide) and therapy (e. LÄS MER

  5. 14. C-Kit as an Oncogenic Tyrosine Kinase - Regulation and Dysregulation of Signaling Pathways

    Författare :Malin Pedersen; Institutionen för translationell medicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : It is well known that increased growth and survival of cancer cells often is a result of dysregulated kinase activity and aberrant kinase signaling. The receptor tyrosine kinase c-Kit and its ligand SCF are contributors to this phenomenon in a variety of human cancers, for example hematological malignancies, germ cell tumors and gastrointestinal stromal tumors. LÄS MER

  7. 15. Aspects on the etiology of esophageal and gastric cancer

    Författare :Mats Lindblad; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Esophageal; gastric; gastric cardia; cancer; cancer register; misclassification; epidemiology; incidence; etiology; estrogen; aspirin; non-steroidal anti-inflammatory drugs; body mass; tobacco; alcohol; adenocarcinoma; squamous-cell carcinoma;

    Sammanfattning : In a global perspective esophageal and gastric cancer present major health concerns, whereas these tumors are comparatively uncommon in most western countries. Striking and hitherto unexplained rising incidence trends of esophageal adenocarcinoma, and moderately increasing rates of gastric cardia adenocarcinoma have recently been reported from several western countries, however. LÄS MER