Sökning: "Gastrointestinal mucosal permeability"

Visar resultat 1 - 5 av 11 avhandlingar innehållade orden Gastrointestinal mucosal permeability.

  1. 1. Gut peptides in gastrointestinal motility and mucosal permeability

    Författare :Md. Abdul Halim; Webb Dominic-Luc; Per M Hellström; Lars Fändriks; Uppsala universitet; []
    Nyckelord :Gut regulatory peptides; Neuropeptides; Gastrointestinal mucosal permeability; Gastrointestinal motility; GLP-1; NPS; ROSE-010;

    Sammanfattning : Gut regulatory peptides, such as neuropeptides and incretins, play important roles in hunger, satiety and gastrointestinal motility, and possibly mucosal permeability. Many peptides secreted by myenteric nerves that regulate motor control are also produced in mucosal epithelial cells. LÄS MER

  3. 2. Gastrointestinal Permeability and Motility in Inflammatory Bowel Disease

    Författare :Anas Kh. Al-Saffar; Per Hellström; Dominic-Luc Webb; Åsa Keita; Uppsala universitet; []
    Nyckelord :Gastrointestinal motility; intestinal permeability; Mucosal; Ghrelin; Medicinsk vetenskap; Medical Science;

    Sammanfattning : Synchronized motility, permeability and secretory (hormones and enzymes) events are integral to normal physiology. Smooth muscle syncytium operates with enteric nervous system (ENS) and endocrine signalling to accommodate, mix and control passage of ingested materials. LÄS MER

  4. 3. Intestinal permeability : a parameter of mucosal dysfunction

    Författare :Pål Lundin; Biologiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Peptide; N-acetylcysteine; Medium-chain glyceride; Mannitol; Macromolecules; Lipid; Kinetics; In vivo; In vitro; In situ; Intestine; Injury; Inflammation; HLA-B27; HCl; Epithelium; Enhancer; dDAVP; 51Cr-EDTA; BSA; Absorption; Albumin; Permeability; Animal physiology; Djurfysiologi;

    Sammanfattning : The gastrointestinal tract has two opposing functions; to absorb nutrients and electrolytes, and to act as a barrier towards hazardous and non-nutritional substances. In the present thesis the barrier function of the gastrointestinal tract was studied in animal models in vivo, in situ and in vitro. LÄS MER

  5. 4. Nitrate, Nitrite and Nitric Oxide in Gastric Mucosal Defense

    Författare :Joel Petersson; Lena Holm; Jon Lundberg; Mia Phillipson; Matthew Grisham; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; dietary nitrate; mucus gel layer; mucosal blood flow; mucus thickness; laser-Doppler flowmetry; mucosal damage; intra-vital microscopy; mucosal permeability; Physiology; Fysiologi;

    Sammanfattning : The human stomach normally contains high levels of bioactive nitric oxide (NO). This NO derives from salivary nitrate (NO3-) that is converted to nitrite (NO2-) by oral bacteria and thereafter non-enzymatically reduced in the acidic gastric lumen to NO. LÄS MER

  7. 5. Regulation of Duodenal Mucosal Barrier Function and Motility : The Impact of Melatonin

    Författare :Anna Sommansson; Markus Sjöblom; Olof Nylander; Oliver Bachmann; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; 51Cr-EDTA; bicarbonate secretion; duodenum; enteric nervous system; enterochromaffin cell; ethanol; hexamethonium; in vivo; mecamylamine; motility; mucosal permeability; parecoxib; rat; Physiology; Fysiologi;

    Sammanfattning : The duodenal mucosa is regularly exposed to acid, digestive enzymes and ingested noxious agents. It is thus critical to maintain a protective barrier to prevent the development of mucosal injury and inflammation, which are often observed in situations when barrier function is impaired. LÄS MER