Sökning: "Galanin"
Visar resultat 6 - 10 av 80 avhandlingar innehållade ordet Galanin.
6. Galanin receptor ligands : agonists and the first antagonists
Sammanfattning : .... LÄS MER
7. Design, Synthesis and Characterization of Galanin Receptor Selective Ligands
Sammanfattning : Galanin is a 29/30 amino acid long bioactive peptide discovered over 30 years ago when C-terminally amidated peptides were isolated from porcine intestines. The name galanin originates from a combination of the first and last amino acids - G from glycine and the rest from alanine. LÄS MER
8. Characterization of galanin receptors using chimeric peptides and site-directed mutagenesis
Sammanfattning : Galanin, a 29 (30) amino acid neuropeptide, is found throughout both the central and peripheral nervous systems. It signals via three receptors, GalR1-3, all belonging to the rhodopsin-like G-protein coupled receptors. Galanin and its receptors have been implicated in a vast variety of biological processes. LÄS MER
9. The galanin type 2 receptor: molecular biological, histochemical and electrophysiological studies
Sammanfattning : In the present thesis, the aim was to probe the distribution and functions of galanin type 2 receptor (GalR2) in the rodent brain. In order to overcome the lack of a reliable antibody to localize GalR2 by immunohistochemistry, we generated a construct which expresses GalR2 tagged with enhanced GFP (EGFP). LÄS MER
10. Neuropeptides and neurotrophic factors in epilepsy: seizure suppressant actions of VEGF, NPY and galanin
Sammanfattning : Epilepsy is a severe chronic neurological disorder, affecting about 1% of the population. The disease is manifested by spontaneous recurrent seizures, caused by hypersynchronized neuronal activity due to imbalance in the brain between the inhibition and excitation. LÄS MER