Sökning: "Galanin"

Visar resultat 1 - 5 av 77 avhandlingar innehållade ordet Galanin.

  1. 1. Galanin : Studies by Modification of the Ligand and the Receptor

    Författare :Anders Juréus; Claes-Göran Östeson; Stockholms universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Other chemistry; Övrig kemi; neurokemi och neurotoxikologi; Neurochemistry and Neurotoxicology;

    Sammanfattning : This thesis is devoted to the deeper understanding of the molecular details of the interaction between the neuropeptide galanin and its target protein, the G-protein coupled 7TM galanin receptor. The enzymatic control of galanin degradation and second messenger systems triggered by galanin receptor activation are also studied. LÄS MER

  2. 2. Galanin : ligand - receptor interactions

    Författare :Malin Berthold; Stockholms universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; NATURAL SCIENCES;

    Sammanfattning : .... LÄS MER

  3. 3. Galanin receptor ligands

    Författare :Johan Runesson; Ülo Langel; Lena Mäler; Stockholms universitet; []
    Nyckelord :Galanin; GALP; GPCR; Agonist; GalR; Chimeric peptide; Inositol phosphate production; Receptor specificity; neurokemi med molekylär neurobiologi; Neurochemistry and Molecular Neurobiology;

    Sammanfattning : In the nervous system galanin primarily displays a modulatory role. The galaninergic system consists of a number of bioactive peptides with a highly plastic expression pattern and three different receptors. The lack of receptor subtype selective ligands and antibodies have severely hampered the charac-terization of this system. LÄS MER

  4. 4. Galanin receptor : studies with site-directed mutagenesis, agonists and antagonists

    Författare :Kalev Kask; Stockholms universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : .... LÄS MER

  5. 5. Galanin receptor ligands : Design, synthesis, characterization and biological effects

    Författare :Kristin Webling; Ülo Langel; Tore Bengtsson; Stockholms universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

    Sammanfattning : Galanin is a 29/30 amino acid long bioactive peptide discovered over 30 years ago when C-terminally amidated peptides were isolated from porcine intestines. The name galanin originates from a combination of the first and last amino acids - G from glycine and the rest from alanine. LÄS MER