Sökning: "Gab 1"

Hittade 4 avhandlingar innehållade orden Gab 1.

  1. 1. Regulation of intracellular signaling events that modulate insulin action

    Författare :Silvia Gogg; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ; insulin; insulin resistance; EGF; Gab 1; insulin receptor substrate; PI3-kinase; Thiazolidinediones; PPARã; insulin signaling; glucose transport; adipose tissue; â-cell.;

    Sammanfattning : Insulin regulates several mechanisms of fundamental importance to the body involving glucose, fat andprotein metabolism. Insulin resistance in skeletal muscle, liver and adipose tissue promotes an increaseddemand for insulin secretion. LÄS MER

  2. 2. Signal transduction in macrophages. Intracellular pathways activated by microbial constituents

    Författare :Sandra Olsson; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicin människa och djur ; Medicine human and vertebrates ; TNF; TLR; dectin-1; lipid rafts; Src; Btk; Macrophages; arachidonate;

    Sammanfattning : Macrophages play an essential role in the defense against infection by phagocytosis and by production of inflammatory mediators. Such mediators are TNF? and eicosanoids. Many microbial agents elicit arachidonate release in macrophages that lead to the formation of eicosanoids. LÄS MER

  3. 3. Pars prior dissertationis academicæ usum theoriæ nexus rerum universalis in philosophia civili delineantis. Quam ... moderante ... Johanne Ihre, ... publico eruditor. examini modeste committit Fridericus Hök, Gab. Filius Calmariensis. In Auditorio Carol. Maj. die III. Martii MDCCL. H. A. M. S., d. 1

    Författare :Johan Ihre; Fridericus Hök; Johan Ihre; Uppsala universitet; []

    Sammanfattning : .... LÄS MER

  4. 4. Cyanide and central nervous system : a study with focus on brain dopamine

    Författare :Gudrun Cassel; Umeå universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CNS; cyanide; dopaminergic system; convulsions; receptor binding; tyrosine hydroxylase; monoamine oxidase; extracellular release; inositol phosphate; GABA; GAD;

    Sammanfattning : The brain is a major target site in acute cyanide intoxication, as indicated by several symptoms and signs. Cyanide inhibits the enzyme cytochrome oxidase. This inhibition causes impaired oxygen utilization in all cells affected, severe metabolic acidosis and inhibited production of energy. LÄS MER