Sökning: "GRN163L"
Hittade 3 avhandlingar innehållade ordet GRN163L.
1. Gene therapy tools: oligonucleotides and peptides
Sammanfattning : Genetic mutations can cause a wide range of diseases, e.g. cancer. Gene therapy has the potential to alleviate or even cure these diseases. LÄS MER
2. Molecular insights into the pathogenesis of B-cell and myeloid malignancies : therapeutic implications
Sammanfattning : Hematological malignancies originate from hematopoietic cells in the bone marrow or the lymphatic system. In this thesis, I study the molecular pathogenesis of Hodgkin lymphoma (HL), mantle cell lymphoma (MCL), and myeloproliferative neoplasms (MPNs), and explore the underlying therapeutic implication in these diseases. LÄS MER
3. Telomeres and telomerase and their functional applications in myeloproliferative neoplasms and acute myeloid leukemia
Sammanfattning : Myeloproliferative neoplasms (MPNs) are a group of diseases characterized by hyperproliferation in the myeloid lineages of the bone marrow, leading to increased levels of circulating mature blood cells from one or more lineages. MPNs consist of polycythemia vera, essential thrombocythemia and primary myelofibrosis. LÄS MER