Sökning: "GHOST 3 cells"

Hittade 3 avhandlingar innehållade orden GHOST 3 cells.

1. 1. HIV-1 infection during pregnancy and in children : significance of HIV-1 variability and the placental barrier

   Författare :Charlotte Casper; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :biological phenotype; genetic subtype; chemokine receptor; coreceptor; mother- to-child transmission; placenta; disease progression; child; pregnancy;

   Sammanfattning : With the global increase in human immunodeficiency virus 1 (HIV-1) infection in women of childbearing age, there has also been an alarming increase in the number of mother-to-child transmissions of HIV-1. Although antiretroviral therapy and Cesarian section have been demonstrated to significantly decrease the vertical transmission rate of, these interventions are not widely available in the developing world. LÄS MER

3. 2. Coreceptor usage and sensitivity to neutralization of HIV-1 and HIV-2

   Författare :Yu Shi; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :HIV-1; HIV-2; pathogenesis; neutralization; coreceptor usage; envelop sequence; glycosylation; U87.CD4 cells; GHOST 3 cells; CCR5; CXCR4;

   Sammanfattning : The aim of this project was to study neutralization and coreceptor use in HIV-1 and HIV-2. The first step was to develop a simple and standardized assay for detection and quantification of HIV- 1 neutralizing activity in human sera. LÄS MER

4. 3. Receptor use of primate lentiviruses

   Författare :Dalma Vödrös; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :HIV; SIV; animal models; receptor use; neutralizing antibodies; CD4-independence;

   Sammanfattning : Human and simian immunodeficiency viruses (HIV and SIV) enter target cells using CD4, the primary cell surface receptor and a secondary receptor, called coreceptor. Coreceptor use of HIV can be related to other biological features of the virus and to the severity of infection as well. LÄS MER