Sökning: "GH treatment"

Visar resultat 21 - 25 av 99 avhandlingar innehållade orden GH treatment.

  1. 21. GH, IGF-1 and insulin in the regulation of lipid and lipoprotein metabolism

    Författare :Fredrik Frick; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Growth-hormone; insulin-like growth factor-I; insulin; lipoprotein lipase; adipose tissue; muscle tissue; VLDL secretion;

    Sammanfattning : It is well known that growth hormone (GH) has profound effects on lipid and lipoprotein metabolism. Insulin-like growth factor-I (IGF-I) is believed to mediate some of the effects of GH via endocrine and paracrine mechanisms. Moreover, both GH and IGF-I are known to influence insulin secretion. LÄS MER

  3. 22. New treatment strategies for growth failure caused by chronic inflammation in children

    Författare :Paola Fernández Vojvodich; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Chronic inflammation during childhood often leads to impaired bone growth and reduced height in adulthood. Interleukin-1β (IL-1β), interleukin-6 (IL-6) and the tumour necrosis factor-α (TNF-α) are pro-inflammatory cytokines up-regulated during chronic inflammation. LÄS MER

  4. 23. Cardiovascular mortality and morbidity in hypopituitary patients and metabolic effects of growth hormone treatment

    Författare :Birgitta Bulow; Lund Medicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; glucose metabolism; growth hormone replacement; growth hormone deficiency; long-term survival; craniopharyngioma; cardiovascular risk factors; Hypopituitarism; cardiovascular mortality; Endocrinology; secreting systems; diabetology; Endokrinologi; sekretion; diabetologi;

    Sammanfattning : Premature atherosclerosis, cardiovascular risk factors and increased cardiovascular mortality have been shown in patients with hypopituitarism on conventional hormone treatment, but without growth hormone (GH) replacement. The aims of paper I-III were to investigate separately the risks for cerebrovascular and cardiac mortality as well as the incidence of cardiovascular disease in patients with hypopituitarism and to assess the long-term prognosis for patients with craniopharyngioma. LÄS MER

  5. 24. GH/IGF-I axis regulation of cardiovascular and neuronal gene expression and function

    Författare :Anna Barlind; Göteborgs universitet; []
    Nyckelord :Growth hormone; rat; hypophysectomy; vascular resistance; gene expression; place learning; Intellicage; hexarelin; CNS; hippocampus; neurogenesis; cell survival; mouse;

    Sammanfattning : Abstract Cardiovascular disease is a major cause of mortality in the Western world. Another important clinical condition is brain damage due to radiation therapy in cancer patients. This has neurological impairments presenting in the survivors. For both these conditions, it is important to develop new therapeutic strategies. LÄS MER

  7. 25. Connexin43 in astroglial gap junctions. Regulation by age, neurotransmitters, GH and IGF-I

    Författare :N David Åberg; Göteborgs universitet; []
    Nyckelord :Connexin43; rat; development; hypophysectomy; primary culture; ; mRNA; gap junction; somatotropin; IGF-I; serotonin; glutamate; ; brain region heterogeneity; calcium wave; astrocyte; astroglial cell; ; gap junctional coupling.;

    Sammanfattning : Connexins form gap junctions that are aqueous pores allowing low-molecular (.... LÄS MER