Sökning: "GH Ha"

Visar resultat 1 - 5 av 6 avhandlingar innehållade orden GH Ha.

  1. 1. Childhood malignant disease and consequences for growth hormone secretion, intellectual function and cardiovascular risk

    Författare :Katarina Link; Lund Medicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Growth hormone deficiency; Insulin sensitivity; Cranial radiotherapy; Neuropsychological performance; Endocrinology; secreting systems; diabetology; Acute Lymphoblastic leukemia; diabetologi; sekretion; Endokrinologi;

    Sammanfattning : In childhood onset growth hormone deficiency (GHD) a reduction in cardiac left ventricular mass (LVMi) and impairment of cardiac systolic function, as well as in glomerular filtration rate (GFR) has been shown. In study I, we showed that a low dose of GH treatment for 10 months resulted in increased LVMi and kidney size. LÄS MER

  2. 2. Down syndrome : Growth and endocrine impact

    Författare :Åsa Myrelid; Jan Gustafsson; Göran Annerén; Ann-Christine Lindgren; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Down syndrome; growth; growth charts; body proportions; growth hormone; thyroid function; metabolism; body composition; cognition; motor development; Downs syndrom; tillväxt; tillväxtkurvor; kroppsproportioner; tillväxthormon; sköldkörtelfunktion; metabolism; kroppssammansättning; kognitiv förmåga; motorisk utveckling; Paediatric medicine; Pediatrisk medicin; pediatrik; Pediatrics;

    Sammanfattning : Down syndrome (DS) is associated with psychomotor retardation, short stature and endocrine dysfunction. Statural growth is a well-known indicator of health. The growth in DS differs markedly from that of other children and there is a 20 cm reduction of final height as compared to target height. LÄS MER

  3. 3. Insulin-like growth factor-I from a perspective of bone regeneration

    Författare :Per Prisell; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :insulin-like growth factor-I; fracture healing; endochondral bone formation; slow release; indomethacin; corticosteroids; hyaluronan; von Kossa;

    Sammanfattning : The insulin-like growth factor I (IGF-I) is produced by osteoblasts and many other cell types. IGF-I is abundant in bone matrix and mediates some of the effects of growth hormone (GH). The present investigations have focused on IGF-I actions during bone regeneration. LÄS MER

  4. 4. Thermostable glycosidases and glycosynthases as biocatalysts in green chemistry applications

    Författare :Tania Pozzo; Bioteknik; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Green chemistry; 3D sturcture; Glycosyl hydrolases; Glycosynthases; Alkyl glucosides; Oligosaccharides; Flavonoids;

    Sammanfattning : The constant need to develop environmental friendly processes using renewable raw materials and to reduce harmful waste production motivates the present investigation focusing on biocatalyst development for enzymatic synthesis, a biotechnological approach in the field of green chemistry. At first, structural functional experiments were made for a β-glucosidase from T. LÄS MER

  5. 5. β-Mannan degradation by gut bacteria - Characterization of β-mannanases from families GH5 and GH26

    Författare :Evelina Kulcinskaja; Biokemi och Strukturbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; glycoside hydrolases; gut microflora; mannan; enzymes; GH26; GH5; β-mannanase;

    Sammanfattning : The human gut flora is important for our well-being. The gut bacteria are able to degrade and metabolize complex carbohydrates. Examples of such carbohydrates are β-mannans. β-Mannans consist of a backbone of β-1,4-linked mannose units and are present in e. LÄS MER