Sökning: "GENE-TRANSFER"
Visar resultat 1 - 5 av 128 avhandlingar innehållade ordet GENE-TRANSFER.
1. Retroviral gene transfer to repopulating hematopoietic cells
Sammanfattning : Hematopoietic stem cells (HSCs) have the capacity to maintain hematopoiesis throughout life. HSCs are ideal targets for permanent gene transfer, as the transgene will be expressed in all the progeny of the gene-modified stem cells. LÄS MER
2. Making Doable Problems within Controversial Science : U.S. and Swedish Scientists’ Experience of Gene Transfer Research
Sammanfattning : This thesis explores how scientists within the controversial scientific field of gene transfer make their research doable. Based on in-depth interviews with gene transfer scientists and key individuals from different regulatory agencies and advisory boards in Sweden and the U.S.A. LÄS MER
3. Treatment of Skin Wounds with Cell Transplantation and Gene Transfer
Sammanfattning : Background: A large number of different wound coverings have been used in order to improve the wound microenvironment, and thus accelerate repair. Since almost two centuries, clinicians and researchers have developed techniques for skin transplantation. LÄS MER
4. Targeted gene transfer in the developing central nervous system using viral vectors
Sammanfattning : Dopamine (DA) is a neurotransmitter that plays a fundamental role in many aspects of normal brain function. The majority of DA neurons in the brain reside in one region ? the midbrain ? and project axonal connections to specific areas. One of the main target regions of the DA system is the striatum. LÄS MER
5. Evolutionary Dynamics of Mutation and Gene Transfer in Bacteria
Sammanfattning : The study of bacterial evolution is fundamental for addressing current problems of antibiotic resistance and emerging infectious diseases and lays a solid foundation for successful and rational design in biotechnology and synthetic biology. The main aim of this thesis is to test evolutionary hypotheses, largely based on theoretical considerations and sequence analysis, by designing scenarios in a laboratory setting to obtain experimental data. LÄS MER