Sökning: "GABA channel"

Visar resultat 6 - 10 av 25 avhandlingar innehållade orden GABA channel.

  1. 6. Novel microfluidic methods for studies of ion channel function

    Författare :Jon Sinclair; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; patch clamp; micro fabrication; ion channels; microfluidics; drug discovery; GABAA< sub> receptors; memory;

    Sammanfattning : .... LÄS MER

  3. 7. Patch-clamp studies of the GABAA receptor using microfluidic methods

    Författare :Maria Millingen; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; ion channel; microfluidics; GABAA receptor;

    Sammanfattning : Ion channels are membrane proteins that passively transport ions. When activated, conformational changes within the protein lead to opening of a channel pore, and the flow of ions causes a change in the membrane potential. This is the fundamental process behind the generation and transduction of nerve impulses. LÄS MER

  4. 8. Studies of ligand- and temperature-gated ion channels using microfluidic methods

    Författare :Maria Millingen; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; solution exchange; desensitization; temperature-gated; ion channel; temperature control; ligand-gated; TRPV1; GABAA receptor; microfluidics;

    Sammanfattning : This thesis describes the studies of the GABAA receptor, a ligand-gated ion channel, and the ligand- and temperature-gated ion channel TRPV1. The desensitization behavior of both of these proteins has been studied for different conditions, using a microfluidic device for superfusion. LÄS MER

  5. 9. Role of GABA and GABAA Channels in T lymphocytes and Stem cells

    Författare :Suresh Kumar Mendu; Bryndis Birnir; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : GABA (gamma-aminobutyric acid) is best known for its physiological function in the central nervous system.  In the brain GABA is the main inhibitory neurotransmitter where it decreases excitability of neurons and neuronal networks. LÄS MER

  7. 10. Glutamate and GABA signalling components in the human brain and in immune cells

    Författare :Amol K. Bhandage; Bryndis Birnir; Gerard P. Ahern; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Neuroscience; Neurovetenskap; Immunologi; Immunology;

    Sammanfattning : Glutamate and γ-aminobutyric acid (GABA) are the principal excitatory and inhibitory neurotransmitters in the central nervous system (CNS). They both can activate their ionotropic and metabotropic receptors. LÄS MER