Sökning: "G2-phase"
Visar resultat 11 - 14 av 14 avhandlingar innehållade ordet G2-phase.
11. A screen for mutations affecting PNS development in Drosophila identifies the trim gene, dappled
Sammanfattning : The peripheral nervous system of Drosophila melanogaster contains a variety of sense organs, ranging from the relatively simple four celled bristle organ to the more complex compound eye. The development of each organ type is well described, providing a useful backdrop for functional studies of genes acting in one or more of the many processes involved in organogenesis. LÄS MER
12. Studying the cell cycle using systems biology and high content characterization of the ubiquitin proteasome system
Sammanfattning : The cell cycle is the process through which our cells grow and divide in a carefully orchestrated and controlled manner. An uncontrolled cell cycle is a basic hallmark of cancer, in which excessive cell growth leads to adverse effects on the tissue- and organ-level. LÄS MER
13. Studies on mechanisms of busulphan cytotoxicity and pharmacokinetics : with special reference to liposomal busulphan
Sammanfattning : Busulphan is an alkylating agent currently used in conditioning regimen prior to stem cell transplantation (SCT). High dose therapy with busulphan has been shown to contribute to transplantation-related toxicities, such as veno-occlusive disease (VOID) and interstitial pneumonia, Previous pharmacodynamic studies have attempted to define a target systemic exposure to busulphan, and thresholds for different side effects. LÄS MER
14. Cyclins on the move : a time and a place for cyclin A2 and cyclin B1 in the human cell cycle
Sammanfattning : The ultimate aim of the cell cycle is to create an identical daughter cell. Therefore, correct progression through the different phases of the cell cycle is crucial to ensure faithful cell division. LÄS MER
