Sökning: "G2-phase"

Visar resultat 1 - 5 av 13 avhandlingar innehållade ordet G2-phase.

  1. 1. Generation of Retinal Neurons : Focus on the Proliferation and Differentiation of the Horizontal Cells and their Subtypes

    Författare :Henrik Boije; Finn Hallböök; Paul Layer; Uppsala universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; FoxN4; Ptf1a; PH3; G2-phase; Cell cycle arrest; Differentiation; Fate; Commitment; Neurogenesis; Follistatin; Neuroscience; Neurovetenskap; Neuroscience; Neurovetenskap;

    Sammanfattning : We have used the chicken retina as a model for investigating cell cycle regulation and cell fate commitment during central nervous system development. This thesis focuses on the characterization of and commitment to the horizontal cell fate in the retina. LÄS MER

  2. 2. Regulation of G2 phase and long-term consequences of DNA damage

    Författare :Anna Won Middleton; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP;

    Sammanfattning : Cell proliferation requires the accurate replication of DNA and equal segregation of replicated genes, important for maintaining the integrity of newly formed cells. At the centre of this process is a series of coordinated events termed ‘the cell cycle’, which ensures cell proliferation proceeds with high fidelity. LÄS MER

  3. 3. Statistical Modelling of Cell Cycle Dynamics Analysis and Interpretation of BrdUrd DNA FCM-Derived Data

    Författare :Sara Larsson Lönn; Matematisk statistik; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; G2 phase duration; DNA replication; flow cytometry; Natural science; Naturvetenskap; S phase duration; DNA distribution; branching processes; cell cycle kinetics;

    Sammanfattning : It it of great importance to increase the knowledge of various cell cycle kinetic parameters and the objective of this thesis is to use stochastic models to interpret Bromodeoxyuridine (BrdUrd) DNA Flow Cytometry (FCM) derived data in order to estimate such parameters. The cell cycle is the process of growth and division that is essential for an organism to increase in size. LÄS MER

  4. 4. Description and prediction of clinical radiosensitivity : Emphasis on normal tissue reactions

    Författare :Roger Tell; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; Radiotherapy; radiosensitivity; normal tissue; thyroid; cell cycle; lung injury;

    Sammanfattning : There is a range in the severity of normal tissue reactions observed when cancer patients receive radiotherapy (RT). The limits of dosage in RT have empirically been set by doses that have caused severe reactions in the most sensitive patients. The understanding of factors governing variations of radiosensitivity is therefore very important in RT. LÄS MER

  5. 5. The cytolethal distending toxin of Haemophilus ducreyi. Prevalence and effects on normal cells

    Författare :Liselott Svensson; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :;

    Sammanfattning : Haemophilus ducreyi is a fastidious Gram-negative bacterium that causes the sexually transmitted disease chancroid. The disease is endemic in many developing countries and occurs as restricted outbreaks in the industrialised part of the world. LÄS MER