Sökning: "G protein-coupled estrogen receptor 1"

Visar resultat 6 - 8 av 8 avhandlingar innehållade orden G protein-coupled estrogen receptor 1.

  1. 6. Estrogen actions in the growth plate cartilage

    Författare :Maryam Iravani; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Estrogens may influence bone growth locally or systemically via the estrogen receptors alpha (ERα), beta (ERβ) and G protein-coupled estrogen receptor 1 (GPER-1). In Paper I, our study showed that the treatment of ovariectomized C57BL/6 mice with a selective ERα agonist 1,3,5-tris(4-hydroxyphenyl)-4-propyl-1H-pyrazole (PPT) reduced growth plate height and hypertrophic zone height suggesting that the effect was induced via ERα. LÄS MER

  2. 7. Role and mechanism of estrogen receptor beta in the physiology of the ovary and colon

    Författare :Madeleine Birgersson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Estrogen regulates a variety of important physiological functions in both males and females, where the regulation of female reproduction and the development of sexual organs are typical examples. The effects of estrogen are predominantly exerted via signaling through the two nuclear receptors estrogen receptor α (ERα) and β (ERβ), or the membrane G protein-coupled estrogen receptor 1 (GPER1). LÄS MER

  3. 8. Hormonal regulation of the primate uterus : effects of hormone treatment and lifestyle intervention

    Författare :Mariana Hulchiy; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :endometrium;

    Sammanfattning : The uterus is a major hormone-responsive reproductive organ in primates. Hormones promote their effect via different pathways. Receptors involved in steroid hormone, thyroid hormone and insulin signaling have been found in the endometrium. LÄS MER