Sökning: "G matrix"

Visar resultat 21 - 25 av 348 avhandlingar innehållade orden G matrix.

  1. 21. Evolutionary dynamics of migration and breeding in wild birds: genetic architecture, sexual conflicts and evolutionary constraints

    Författare :Maja Tarka; Biologiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; quantitative genetics; heritability; intralocus sexual conflict; antagonistic selection; QTL; G-matrix; wing length; arrival date; migration; geolocator; bird; Acrocephalus arundinaceus;

    Sammanfattning : Our knowledge of the evolutionary potential of traits involved in different selective episodes, especially in natural populations, is still limited. This is true for questions such as the genetic basis and inheritance of traits, how natural and sexual selection acts on them, and how selective conflicts influence the evolutionary response to selection. LÄS MER

  2. 22. Matrix degrading proteases in vascular disease

    Författare :Sofia Jormsjö-Pettersson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; Atherosclerosis; abdominal aortic aneurysm; MMP; cathepsin; polymorphism; in vitro; proteases; extracellular matrix.;

    Sammanfattning : Diverse processes of vascular disease including lesion growth, plaque rupture and abdominal aortic aneurysm formation are influenced by protease expression. Arteries undergo compensatory remodelling when the mechanical forces that are imposed on them are altered. LÄS MER

  3. 23. Laminin G Domains, their Receptors, and Activation of Intracellular Pathways

    Författare :Hao Yu; Klinisk minnesforskning; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biomedicinska vetenskaper allmänt ; General biomedical sciences; cell-matrix interaction; signaling; receptor; Basement membrane; laminin;

    Sammanfattning : Basement membranes are sheet like structures underlying epithelial, endothelial, adipocytes, muscle and peripheral nerve cells. Laminins are an important family of basement membrane proteins implicated in various biological functions through their interactions with cell surface receptors. Laminins are trimers composed of a, b and g chains. LÄS MER

  4. 24. Comparative network analysis of human cancer: sparse graphical models with modular constraints and sample size correction

    Författare :José Sánchez; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; NATURAL SCIENCES; Inverse covariance matrix; precision matrix; graphical models; high-dimension; low-sample; networks; sparsity; fused lasso; elastic net; cancer.; fused lasso;

    Sammanfattning : In the study of transcriptional data for different groups (e.g. cancer types) it's reasonable to assume that some dependencies between genes on a transcriptional or genetic variants level are common across groups. Also, that this property is preserved locally, thus defining a modular structure in the model networks. LÄS MER

  5. 25. Determination of the Environmental Fate of Drug Substances and the Matrix Effects of Complex Samples in SFC/ESI-MS

    Författare :Alfred Haglind; Curt Pettersson; Mikael Hedeland; Torbjörn Arvidsson; Deirdre Cabooter; Uppsala universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; SFC-MS; matrix effect; ion cluster; Supercritical fluid chromatography; ESI; chiral separation; transformation products; LC-QToF; wetland microcosms; Analytical Pharmaceutical Chemistry; Analytisk farmaceutisk kemi;

    Sammanfattning : Awareness of the potential problems caused by drug compounds in the environment has increased over the last decade, both among researchers and with the public. This thesis describes the development of analytical methods and their application to wetlands constructed for purification of wastewater from e.g. drug compounds. LÄS MER