Sökning: "Göran Widmalm"
Visar resultat 16 - 20 av 31 avhandlingar innehållade orden Göran Widmalm.
16. Carbohydrate Structural Studies. Towards Automatic Structure Determination
Sammanfattning : .... LÄS MER
17. Computer-Assisted Carbohydrate Structural Studies and Drug Discovery
Sammanfattning : Carbohydrates are abundant in nature and have functions ranging from energy storage to acting as structural components. Analysis of carbohydrate structures is important and can be used for, for instance, clinical diagnosis of diseases as well as in bacterial studies. The complexity of glycans makes it difficult to determine their structures. LÄS MER
18. Synthesis and analysis of carbohydrates related to bacterial polysaccharides
Sammanfattning : The outer surface of bacteria is composed of around 75% carbohydrates, which are vital for the bacteria to survive and communicate with the host biological system. The thesis discusses different properties of carbohydrates that are essential for understanding the bacterial behavior in biological systems. LÄS MER
19. Structural and Interaction Studies of Bacterial Polysaccharides by NMR Spectroscopy
Sammanfattning : An introduction to bacterial polysaccharides and the methods for structural determination are described in the first two parts of the thesis.In a structural elucidation of bacterial polysaccharides NMR experiments are important as is component analysis. A short description of immunochemical methods such as enzyme immunoassays is included. LÄS MER
20. Structural Studies of O-antigen polysaccharides, Synthesis of 13C-labelled Oligosaccharides and Conformational Analysis thereof, using NMR Spectroscopy
Sammanfattning : In order to understand biological processes, to treat and diagnose diseases, find appropriate vaccines and to prevent the outbreak of epidemics, it is essential to obtain more knowledge about carbohydrate structures. This thesis deals with structure and conformation of carbohydrates, analysed by NMR spectroscopy and MD simulations. LÄS MER