Sökning: "Göran Widmalm"
Visar resultat 11 - 15 av 31 avhandlingar innehållade orden Göran Widmalm.
11. Structural and Conformational Analysis of Bacterial Polysaccharides using NMR Spectroscopy
Sammanfattning : Carbohydrates is one of the three classes of biomolecules found in nature. It is the most common one in comparison to the other two classes, lipids and proteins. However, this simple categorization does not reflect the reality since carbohydrates often are covalently linked to e.g. LÄS MER
12. The sweet side of molecular structure : NMR spectroscopic studies of glycans and their interactions with proteins
Sammanfattning : In this thesis, within the topic of bioorganic chemistry, the molecular structure of carbohydrates has been studied. Carbohydrates, or glycans, are ubiquitous biomolecules exhibiting a wide range of biological roles. LÄS MER
13. Exploring the structure of oligo- and polysaccharides : Synthesis and NMR spectroscopy studies
Sammanfattning : A deeper understanding of the diversity of carbohydrates and the many applications of oligo- and polysaccharides found in nature are of high interest. Many of the processes involving carbohydrates affect our everyday life. This thesis is based on six papers all contributing to an extended perspective of carbohydrate property and functionality. LÄS MER
14. Structure, dynamics and interactions of biomolecules : Investigations by NMR spectroscopy and computational methods
Sammanfattning : In this thesis, the structure, dynamics and interactions of proteins and carbohydrates are investigated using mainly NMR spectroscopy and computer simulations. Oligosaccharides representing a Salmonella O-antigen have been synthesized and their dynamic behavior and interaction with the bacteriophage P22 tail-spike protein have been studied by NMR spectroscopy, MD and docking simulations. LÄS MER
15. Synthesis, structure and conformation of oligo- and polysaccharides
Sammanfattning : Carbohydrates are a complex group of biomolecules with a high structural diversity. Their almost omnipresent occurrence has generated a broad field of research in both biology and chemistry. This thesis focuses on three different aspects of carbohydrate chemistry, synthesis, structure elucidation and the conformational analysis of carbohydrates. LÄS MER