Sökning: "Gérard Hopfgartner"

Hittade 2 avhandlingar innehållade orden Gérard Hopfgartner.

1. 1. Quantitative Bioanalysis : Liquid separations coupled to targeted mass spectrometric measurements of bioactive compounds

   Författare :Björn Arvidsson; Jonas Bergquist; Magnus Wetterhall; Gérard Hopfgartner; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Analytical chemistry; Method development; Enhanced microdialysis; Column switching; Liquid chromatography; Capillary electrophoresis; Electrospray ionization; Mass spectrometry; Triple quadrupole; Time-of-flight; Quantitation; Validation; Analytisk kemi;

   Sammanfattning : Performing quantitative analysis of targeted bioactive compounds in biological samples, such as blood plasma, cerebrospinal fluid or extracts from pig liver, put high demands on the ruggedness of the method acquiring the results. In addition to the complexity of the sample matrix, the bioactive compounds targeted for analysis usually have low levels of natural abundance, further increasing the demand on the analytical method sensitivity. LÄS MER

3. 2. Analytical method development in liquid chromatography- mass spectrometry based metabolomics

   Författare :Ida Erngren; Mikael Hedeland; Curt Pettersson; Torbjörn Arvidsson; Gérard Hopfgartner; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Analytical pharmaceutical chemistry; metabolomics; liquid chromatography; mass spectrometry; hydrophilic interaction liquid chromatography; Analytical Pharmaceutical Chemistry; Analytisk farmaceutisk kemi;

   Sammanfattning : Metabolomics is the analytical field which aims at analyzing all small molecules, metabolites, in a biological system simultaneously. Currently no analytical methods are able to capture the entire metabolome, therefore, the analytical methods are often developed to be as general as possible. LÄS MER