Sökning: "Fysikalisk biologi"

Visar resultat 21 - 25 av 70 avhandlingar innehållade orden Fysikalisk biologi.

  1. 21. Peptide-Liposome Model Systems for Triggered Release

    Författare :Camilla Skyttner; Daniel Aili; Karin Enander; Fredrik Höök; Linköpings universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : Liposomes are widely used in drug delivery to improve drug efficacy and to reduce side effects. For liposome-encapsulated drugs to become bioavailable and provide a therapeutic effect they must be released, which typically is a slow process that primarily relies on passive diffusion, liposome rupture or endocytotic uptake. LÄS MER

  3. 22. Biomolecule Trapping With Stimuli-Responsive Polymer Coated Nanostructures

    Författare :Justas Svirelis; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; biomolecule transportation; protein interaction; polymer brushes; quartz crystal microbalance with dissipation monitoring; fluorescence microscopy; Poly N-Isopropylacrylamide ; surface plasmon resonance; poly ethylene glycol ;

    Sammanfattning : Trapping biomolecules in nanosized gaps is of great interest in novel systems for single molecule analysis and membranes, which filter biomolecules. Current platforms are lacking in full functionality to facilitate biomolecule trapping and transport in their native environment and without covalent tethering to surfaces. LÄS MER

  4. 23. Methods for elucidating membrane protein structure and function

    Författare :Carolina Trkulja; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; patch clamp; antibodies; mass spectrometry; ion channels; proteomics; fluorescence; TRPV1; cholesterol.; limited proteolysis; Membrane proteins;

    Sammanfattning : Elucidation of the structure-function relationship of membrane proteins increases our understanding of many biological processes, both physiological and pathological. However, membrane proteins have been notoriously difficult to study, having part of their structure embedded into the lipid cell membrane. LÄS MER

  5. 24. Biophysical chemistry of the ALS-associated protein SOD1 : Implications for folding, aggregation and in-cell behaviour

    Författare :Fan Yang; Mikael Oliveberg; Per Jemth; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; SOD1 ALS folding in-cell NMR aggregation; Biochemistry; biokemi;

    Sammanfattning : Biophysical chemistry deals with the structural behavior, properties and molecular function of biological macromolecules. A long-standing challenge is here to establish how these macromolecular features change upon transfer from simplified conditions in vitro to the crowded and molecularly complex environment of live cells. LÄS MER

  7. 25. Hemicelluloses from Agricultural and Forestry Crops Isolation, Characterisation, and Enzymatic Hydrolysis

    Författare :Alexandra Andersson; Biokemi och Strukturbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Proteiner; enzymologi; Physical chemistry; Fysikalisk kemi; enzymology; hydrogels; Plant biochemistry; Växtbiokemi; Proteins; a-galactosidase; b-mannanase; hemicellulase; corn fibre; barley husks; spruce; size-exclusion chromatography; arabinoxylan; microwave irradiation; steam pretreatment; membrane filtration; hemicellulose; galactoglucomannan;

    Sammanfattning : Hemicelluloses are tremendous sources of renewable raw materials, which utilisation have the potential to be highly increased in the future. Hemicelluloses are among the major groups of compounds in plant cell walls, together with cellulose and lignin. These three components are closely associated, making them difficult to separate from each other. LÄS MER