Sökning: "Functional integration"

Visar resultat 1 - 5 av 328 avhandlingar innehållade orden Functional integration.

  1. 1. Functional association networks for disease gene prediction

    Författare :Dimitri Guala; Erik L L Sonnhammer; Hjalmar Brismar; Yves Moreau; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; network biology; biological networks; network prediction; functional association; functional coupling; network integration; functional association networks; genome-wide association networks; gene networks; protein networks; fret; functional enrichment analysis; network cross-talk; pathway annotation; gene prioritisation; network-based gene prioritization; benchmarking; Biochemistry towards Bioinformatics; biokemi med inriktning mot bioinformatik;

    Sammanfattning : Mapping of the human genome has been instrumental in understanding diseasescaused by changes in single genes. However, disease mechanisms involvingmultiple genes have proven to be much more elusive. Their complexityemerges from interactions of intracellular molecules and makes them immuneto the traditional reductionist approach. LÄS MER

  3. 2. Politisk integration och gränsöverskridande regionbildning i Europa

    Författare :Anders Östhol; Umeå universitet; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; political integration; integration theory; policy networks; cross-border cooperation; régionalisation; region-building; institutionalization; multi-level dependence;

    Sammanfattning : This study starts out with the hypothesis that the integration process in Europe is connected to cross-border régionalisation, a process which supports the institutionalization of subnational cross-border cooperation - region-building. Cross-border régionalisation is characterized by the decentralisation of vertical links and enhanced opportunities for horizontal links across state borders. LÄS MER

  4. 3. Mechatronics engineering : New requirements on cross-functional integration

    Författare :Niklas Adamsson; Margareta Norell Bergendahl; Eva Lovén; KTH; []
    Nyckelord :Mechatronics engineering; product development; multidisciplinary teamwork; organizational integration; cooperation; TECHNOLOGY; TEKNIKVETENSKAP;

    Sammanfattning : Several industrial sectors experience an increased reliance on mechatronic systems as electronics and software are being embedded into the traditional mechanical systems of these industries. Important challenges within mechatronics engineering comes from management of multi-disciplinary development project teams and the highly complex scope of problems, which in turn require extensive coordination and integration, both in terms of technical and organisational matters. LÄS MER

  5. 4. Tool Integration and Safety : A Foundation for Analysing the Impact of Tool Integrationon Non-functional Properties

    Författare :Fredrik Asplund; Martin Törngren; Jad El-khoury; Jakob Axelsson; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Tool Integration; Integrated Development Environments; Embedded Systems; Safety Standards; Certification; Qualification; Systems Thinking; System Safety; STAMP; STPA;

    Sammanfattning : The increasing complexity of embedded systems development is becoming difficult to handle with development environments based on disjoint engineering tools. Support for interactions between various engineering tools, especially through automated means, has therefore received an increased amount of attention during the last few years. LÄS MER

  7. 5. Dynamic Knowledge Integration : A field study of an Information Systems Development Project

    Författare :Linnéa Wahlstedt; Lars Lindkvist; Tim Brady; Linköpings universitet; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Knowledge integration process; collective heuristic; development projects; problem-solving; knowledge diversity; field study; Kunskapsintegrationsprocess; kollektiv heuristik; utvecklingsprojekt; problemlösning; kunskapsbaserade olikheter; fältstudie;

    Sammanfattning : Current research on knowledge integration offers valuable structural analyses of factors that influence knowledge integration, performance outcomes, and knowledge integration mechanisms. Less attention has been paid to how knowledge integration is carried out over time in cross-functional development projects. LÄS MER