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1. 1. Sophocles sorgespel. 2. delen. Med phil. facult. tillstånd under inseende af Vilhelm Fredrik Palmblad ... till offentlig granskning framstäld af Otto Pontén af Smålands nation. å Gustavianska lärosalen den 12 dec. 1838 f. m

   Författare :Vilhelm Fredrik Palmblad; Otto Pontén; Vilhelm Fredrik Palmblad; Uppsala universitet; []
   Nyckelord :HUMANIORA; HUMANITIES;

   Sammanfattning : .... LÄS MER

3. 2. Growth characteristics and p53 alterations in human basal cell cancer : between bewildering basics & BCC biology

   Författare :Fredrik Pontén; Uppsala universitet; []
   Nyckelord :MEDICINE; MEDICIN;

   Sammanfattning : .... LÄS MER

4. 3. Biomarker Discovery in Cutaneous Malignant Melanoma : A Study Based on Tissue Microarrays and Immunohistochemistry

   Författare :Margrét Agnarsdóttir; Fredrik Ponten; Peter Naredi; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; antibody-based proteomics; automated analysis; biomarker; immunohistochemistry; malignant melanoma; survival; tissue microarray; Tumour biology; Tumörbiologi; Pathology; Patologi; Molecular medicine; Molekylär medicin; Medical Science; Medicinsk vetenskap; Pathology; Patologi;

   Sammanfattning : The incidence of cutaneous malignant melanoma has increased dramatically in Caucasians the last few decades, an increase that is partly explained by altered sun exposure habits. For the individual patient, with a localized disease, the tumor thickness of the excised lesion is the most important prognostic factor. LÄS MER

5. 4. Validation of antibodies for tissue based immunoassays

   Författare :Sandra Andersson; Anna Asplund; Fredrik Pontén; Kenneth Wester; Mike Taussig; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Antibody validation; Conjugation; Estrogen receptor-beta; IHC; ISH; Lymphohematopoietic tissues; Proteomic; RNAseq; TMA; Transcriptomic; Patologi; Pathology;

   Sammanfattning : In situ protein detection in human tissues using antibodies reveals the cellular protein localization, and affinity-based proteomic studies can help to discover proteins involved in the development of diseases. However, antibodies often suffer from cross-reactivity, and the lack of positive and negative tissue controls for uncharacterized proteins complicates the mapping of the proteome. LÄS MER

7. 5. Molecular Analysis of Normal Human Skin and Basal Cell Carcinoma Using Microdissection Based Methods

   Författare :Anna Asplund; Fredrik Pontén; Uffe Birk Jenssen; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pathology; skin; basal cell carcinoma; microdissection; X-chromosome inactivation; Patologi; Pathology; Patologi;

   Sammanfattning : The aim of this thesis was to gain further insight into the biology of normal human skin and basal cell carcinoma (BCC). Morphology in combination with microdissection was used as primary tool for sampling. LÄS MER