Sökning: "Fredrik Johansson Swartling"

Hittade 2 avhandlingar innehållade orden Fredrik Johansson Swartling.

1. 1. Integrative modeling of intratumoral heterogeneity, plasticity and regulation in nervous system cancers

   Författare :Ida Larsson; Sven Nelander; Fredrik Swartling; Patrik Johansson; Itay Tirosh; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Nervous system cancer; Glioblastoma; Heterogeneity; Plasticity; Mathematical modeling; Oncology; Onkologi;

   Sammanfattning : The adult brain tumor glioblastoma (GBM) is characterized by short survival and a lack of efficient treatments. Median survival is 15 months from time of diagnosis and the 5-year survival rate is only 7 %. LÄS MER

3. 2. Heparan Sulfate Proteoglycans in Brain Tumor Development

   Författare :Argyris Spyrou; Karin Forsberg Nilsson; Fredrik Johansson Swartling; Jöns Hilborn; John Couchman; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; glioma; pediatric brain tumors; heparanase; NDST1; heparan sulfate proteoglycans; CD24; glycosaminoglycan mimetics; Biology with specialization in Molecular Cell Biology; Biologi med inriktning mot molekylär cellbiologi;

   Sammanfattning : Malignant brain tumors are aggressive neoplasms that remain challenging to treat in spite of their detailed molecular characterization. Both adults and children may suffer from brain tumors, which, if not lethal, can cause severe long-term and devastating side effects. LÄS MER