Sökning: "Follicular thyroid cancer"

Visar resultat 1 - 5 av 17 avhandlingar innehållade orden Follicular thyroid cancer.

  1. 1. Thyroid cancer : studies on etiology and prognosis

    Författare :Arne Hallquist; Lennart Hardell; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Thyroid cancer; prognostic factors; etiology; occupation; medical ionizing radiation; reproductive; and family factors;

    Sammanfattning : Thyroid cancer constitutes about 1% of all malignant tumours and the incidence is increasing in Sweden. It is rare in children before the age of 10. During puberty the female to male ratio increases to be two to three times more common in females. The ratio remains constant until menopause and thereafter declines. LÄS MER

  3. 2. Reversal of thyroid dedifferentiation and an invasive phenotype by small molecule kinase inhibitors: an experimental study on normal and malignant cells

    Författare :Camilla Ingeson-Carlsson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; thyroid; cancer; NIS; MAPK; PI3K; BRAFV600E; migration; 3D culture;

    Sammanfattning : Refractoriness to I-131 in dedifferentiated thyroid cancer is a great concern that restricts radioiodine therapy. There is also a lack of knowledge in understanding the mechanisms leading to repressed sodium iodide symporter (NIS) expression and impaired iodide uptake in tumor cells. LÄS MER

  4. 3. Molecular Screening for Target Discovery in Cancer

    Författare :Mårten Fryknäs; Anders Isaksson; Ulf Pettersson; Hugh Salter; Uppsala universitet; []
    Nyckelord :Genetics; Cancer; Drug resistance; Microarray; High-throughput screening; Genetik;

    Sammanfattning : Cancer is one of the major causes of death in the western world. Resistance to anti-cancer drugs and diagnostic difficulties are major obstacles to successful treatment. LÄS MER

  5. 4. Regulation of apoptosis in the thyroid epithelium

    Författare :Abeba Demelash; Göteborgs universitet; []
    Nyckelord :Thyroid; Apoptosis; Caspase; Calpain; Hydrogen peroxide; TGF-beta; Staurosporine; Selenium; Cytochrome c;

    Sammanfattning : Apoptosis or programmed cell death allows the multicellular organism to remove cells that are in excess or potentially dangerous. Apoptosis has to be strictly controlled, yet inappropriately activated or suppressed apoptototic may contribute to a variety of diseases, including cancer, autoimmune disorders and neurodegenerative conditions. LÄS MER

  7. 5. Telomerase related studies in thyroid cancer

    Författare :Martin Harper Hysek; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Follicular thyroid neoplasms are diagnostically challenging. On histologic evaluation, it can be difficult, resource-consuming, and observer-dependent to pinpoint the exact location of capsular or vascular invasion. LÄS MER