Sökning: "Folkhälsomedicinska forskningsområden"
Visar resultat 16 - 20 av 28 avhandlingar innehållade orden Folkhälsomedicinska forskningsområden.
16. Endogenous hormones in the etiology of ovarian and endometrial cancers
Sammanfattning : The main purpose of this thesis was to examine the relationship of pre-diagnostic circulating levels of sex-steroids (androgens and estrogens), sex hormone binding globuline (SHBG), insulin-like growth factor-I (IGF-I), IGF binding proteins (BP) and C-peptide (as a marker of pancreatic insulin secretion) with risk of ovarian and endometrial cancer. Additionally, the interrelationships of body mass index (BMI), sex-steroids, IGF-I and IGFBP-3 were examined. LÄS MER
17. Improving the prevention of sexually transmitted infections (STIs) : a study using Chlamydia trachomatis as a model infection
Sammanfattning : Despite the current preventive strategies sexually transmitted infections (STIs) are rising. This thesis presents a model with the aim of improving the prevention of STIs. Chlamydia being the most common STI in Sweden serves as a model infection. The presented model is based on five performed studies. LÄS MER
18. Social inequity in health : Explanation from a life course and gender perspective
Sammanfattning : Background: A boy child born in a Gothenburg suburb has a life expectancy that is nine years shorter than that of another child just 23 km away, and among girls the difference is five years. There is no necessary biological reason to this observed difference. LÄS MER
19. Modeling Amyloid-β Pathology in Alzheimer’s Disease Using the Arctic Mutation
Sammanfattning : The Arctic mutation in the Amyloid-β (Aβ) domain of the Amyloid-β precursor protein (APP) causes Alzheimer’s disease (AD) and confers unique biochemical characteristics to Aβ peptides. The aims of this thesis were to evaluate a transgenic model with the Arctic mutation, and to use it to gain new insights into the mechanisms of early (pre-plaque) and late-stage Aβ pathogenesis in AD. LÄS MER
20. Lone parenting, socioeconomic conditions and severe ill-health : longitudinal register-based studies
Sammanfattning : The general aims of this dissertation are to analyse how family situation, and especially lone parenting, influence health and life chances in Sweden and the extent to which possible relations are influenced by socioeconomic circumstances and health selection. In two population-based cohort studies we analysed overall and cause-specific mortality (1991-95), and also severe morbidity (1991-94) from different causes among lone mothers in comparison with mothers with partners. LÄS MER