Sökning: "Fluorimetric assay"

Hittade 4 avhandlingar innehållade orden Fluorimetric assay.

  1. 1. Fluorimetric Bioprobe Based on DNA-dye Intercalation - Application in Enviromental and Clinical Monitoring

    Detta är en avhandling från Lund University

    Författare :Yang Liu; Lunds universitet.; Lund University.; [2007]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Bioteknik; Biotechnology; Biokemisk teknik; Biochemical technology; Antibiotics; Toxic aromatic compounds; Doxorubicin; High throughput screening; Fluorimetric assay; DNA;

    Sammanfattning : Nucleic acids have many unique structural features that offer reliable means of recognizing and monitoring many compounds of medical or environmental importance. In recent years, there has been an enormous increase in the use of nucleic acids as a tool to determine the chemical compounds of environmental and clinical interest and the major research activities in these areas have been directed towards the design of sequence-selective biosensors based on hybridization. LÄS MER

  2. 2. Direct injection of plasma samples into restricted-access media precolumns for drug analysis in column-switching systems

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Zuoxiang Yu; Uppsala universitet.; [1997]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical chemistry; Farmaceutisk kemi; PHARMACY Pharmaceutical chemistry; FARMACI Farmaceutisk kemi; analytisk farmaceutisk kemi; Analytical Pharmaceutical Chemistry;

    Sammanfattning : This thesis focuses on the theoretical and practical aspects of using column-switching systems for direct injection of plasma samples to assay drugs at ng/ml levels. The systems utilized a restricted-access media (RAM) precolumn for the sample clean-up and trace enrichment. LÄS MER

  3. 3. Temporal events in neuronal differentiation and cell death : expression and processing of the Alzheimer's amyloid precursor protein family and a protein at the nuclear pore

    Detta är en avhandling från Stockholm : Dep. of Neurochemistry, Stockholm University

    Författare :Marie Beckman; Stockholms universitet.; [2003]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICINE Chemistry Neurochemistry; MEDICIN Kemi Neurokemi; Neurochemistry and Neurotoxicology; neurokemi och neurotoxikologi;

    Sammanfattning : The present study had two major objectives: 1) to elucidate the involvement of Alzheimer’s amyloid precursor protein (APP) family in neuronal differentiation, and the effect of the Alzheimer’s disease (AD)-linked mutation APPV642I on signal transduction; 2) to investigate the fate of the nuclear pore complex protein POM121 during apoptosis and to examine the possibility of using green fluorescent protein (GFP)-labelled POM121 as a non-invasive sensor of apoptosis in living (non-fixed) cells.APP is the parent protein of the b-amyloid peptide, which is the major peptide constituent in the “senile plaques” of AD. LÄS MER

  4. 4. Microsomal glutathione transferase : studies on the kinetic mechanism, species variety, binding properties and substrate measurement

    Detta är en avhandling från Stockholm : Karolinska Institutet, Institute of Enviromental Medicine

    Författare :Tie-Hua Sun; Karolinska Institutet.; Karolinska Institutet.; [1999]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Microsomal glutathione transferase (MGST) is a membrane bound detoxification enzyme, which has been purified from different species including rat, mouse, human, frog, and fish. The rat MGST1 is localized predominantly in the liver microsomes and the outer mitochondrial membrane. LÄS MER