Sökning: "Flow Cytometry"
Visar resultat 16 - 20 av 390 avhandlingar innehållade orden Flow Cytometry.
16. Applications of in situ proximity ligation assays for cancer research and diagnostics
Sammanfattning : In the field of cancer research and diagnostics it is crucial to have reliable methods for detecting molecules involved in the disease. New and better methods for diagnostics, prognostics and drug delivery therefore remain a permanent aim. LÄS MER
17. Investigations of Hematopoietic Stem Cells and Their Age-Associated Alterations
Sammanfattning : The hematopoietic stem cell (HSC) has and continues to be extensively investigated, and represents by far the most studied somatic stem cell. Development of various experimental technologies, including fluorescence activated cell sorting (FACS), have been crucial for research advancements within the hematopoietic field. LÄS MER
18. Heterogeneity of leukemic cells with regard to daunorubicin accumulation and efflux : potential role in drug resistance
Sammanfattning : Cellular resistance to chemotherapy is a major cause of treatment failure in acute myelocytic leukemia (AML) and other malignancies. Drug resistance is multifactorial; the most studied mechanism being multidrug resistance (MDR), mediated by the P-glycoprotein (PPG), a transmembrane transport protein with a pump function, encoded by the mdr 1 gene. LÄS MER
19. High Content Analysis of Proteins and Protein Interactions by Proximity Ligation
Sammanfattning : Fundamental to all biological processes is the interplay between biomolecules such as proteins and nucleic acids. Studies of interactions should therefore be more informative than mere detection of expressed proteins. Preferably, such studies should be performed in material that is as biologically and clinically relevant as possible, i.e. LÄS MER
20. Congenital Dyserythropoietic Anemia type III (CDA III) : diagnostics, genetics and morbidity
Sammanfattning : The Congenital Dyserythropoietic Anemias (CDA) are rare hereditary hemolytic disorders with large bi- to multi-nucleated erythroblasts in the bone marrow. Hemolysis is negative in a direct antiglobulin test (DAT). Based on morphology and clinical picture, three major forms of CDAs, type I, II, and III have been defined. LÄS MER