Sökning: "Fine-tuning"
Visar resultat 1 - 5 av 126 avhandlingar innehållade ordet Fine-tuning.
1. Exotic Decays of Vector-Like Quarks and Development of a Test Procedure for the ITk Strip Module at the ATLAS Detector for the HL-LHC
Sammanfattning : The naturalness problem of the Standard Model (SM) challenges our understanding of the origin of mass. Several theories have been proposed to tackle the problem, one of them is the Composite Higgs Model (CHM) where the Higgs boson of the SM is not an elementary scalar but instead a composite object bound at a confinement scale of a TeV. LÄS MER
2. Deciphering and fine-tuning of myeloid cells in CNS demyelinating conditions
Sammanfattning : Demyelination in the central nervous system (CNS) is a characteristic of various neurological disorders, such as multiple sclerosis (MS), neuromyelitis optica (NMO), subacute combined degeneration (SCD), tabes dorsalis (syphilitic myelopathy), and more. Although the causes vary, CNS demyelination is often associated with a significant buildup of inflammatory activated myeloid cells, mainly consisting of CNS resident microglia and infiltrating monocyte-derived macrophages. LÄS MER
3. Fine-tuning of the catalytic activity and selectivity of palladium pincer complexes
Sammanfattning : This thesis is focused on optimization of the catalytic properties of so-called pincer complexes. This work involved synthesis of a large variety of palladium pincer complexes, which were applied in various organic transformations. LÄS MER
4. Selection and design in antibody phage display
Sammanfattning : The immune system is an important part of the physiology of higher organisms. In the immune system antibodies play a key role in neutralizing and clearing potentially lethal threats from the environment. The importance of antibodies in the immune system has made them come to the attention as a tool in chemistry and medicine. LÄS MER
5. Transcriptional regulation of miRNA-212 and miRNA-132 and their fine-tuning function of beta cell insulin secretion
Sammanfattning : Type 2 diabetes is characterized by hyperglycemia due to insulin resistance in the target tissue and insufficient insulin secretion from the beta cells. Finding new mechanisms and pathways involved in the regulation of insulin secretion from the pancreatic beta cells is of great importance. LÄS MER