Sökning: "Filip J. Larsen"

Hittade 4 avhandlingar innehållade orden Filip J. Larsen.

  1. 1. Dietary inorganic nitrate : role in exercise physiology, cardiovascular and metabolic regulation

    Författare :Filip J. Larsen; Jon Lundberg; Eddie Weitzberg; Björn Ekblom; Victor M Darley-Usmar; Gymnastik- och idrottshögskolan; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Medicin Teknik; Medicine Technology;

    Sammanfattning : Nitric oxide (NO) is a ubiquitous signaling molecule with a vast number of tasks in the body, including regulation of cardiovascular and metabolic function. A decreased bioavailability of NO is a central event in disorders such as hypertension and metabolic syndrome. LÄS MER

  3. 2. The significance of mitochondrial respiratory function in regulating oxygen uptake and performance in humans

    Författare :Daniele A. Cardinale; Filip J Larsen; David Bishop; Gymnastik- och idrottshögskolan; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mitochondria; OXPHOS; p50mito; mitochondrial oxygen affinity; oxygen extraction; sex difference; hyperoxia; training; muscle metabolism; performance; HIIT; Medicin Teknik; Medicine Technology;

    Sammanfattning : The mitochondrion is one of the most fascinating organelles of our cells which has kept and keeps researchers busy in studying its origin, the complex morphology, the numerous functions, the rapid adaptations to a variety of stimuli and its role in health and disease. Exercise challenges cellular homeostasis and skeletal muscle mitochondria greatly adapt to repeated bouts of exercise by increasing mitochondrial respiratory function and content to match energy requirements and to better sustain future perturbations induced by muscle contractions. LÄS MER

  4. 3. Skeletal muscle fiber types in man : With special reference to anabolic signaling and mitochondrial bioenergetics

    Författare :Sebastian Edman; William Apro; Filip J Larsen; Abram Katz; Leigh Breen; Gymnastik- och idrottshögskolan; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mTORC1; THRIFTY; fiber type identification; muscle growth; aging; sarcopenia; mitochondrial function; oxphos; metabolism; Medicin Teknik; Medicine Technology;

    Sammanfattning : Human skeletal muscle consists of a mixture of slow-twitch (type I) and fast-twitch (type II) fibers. The type I fibers are endurance-oriented, with a metabolic system and infrastructure that supports aerobic metabolism. LÄS MER

  5. 4. Exercising on the edge: mitochondrial and metabolic responses to intense training

    Författare :Mikael Flockhart; Filip J Larsen; Eva Blomstrand; Nikolai Baastrup Nordsborg; Gymnastik- och idrottshögskolan; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Exercise; training; mitochondria; performance; glucose tolerance; proteins; oxygen uptake; metabolism; cycling; Medicin Teknik; Medicine Technology;

    Sammanfattning : Exercise and exercise training induces several physiological adaptations that increase the oxidative capacity of the muscles and improve glucose regulation. While the positive metabolic adaptations and effects on glucose regulation after exercise and exercise training have been extensively studied, negative outcomes have not. LÄS MER