Sökning: "Filaggrin"
Visar resultat 1 - 5 av 16 avhandlingar innehållade ordet Filaggrin.
1. Studies on the pH gradient in normal and ichthyotic human skin
Sammanfattning : In search for pathogenetic mechanisms underlying hyperkeratosis, we examined the pH gradient across the stratum corneum in normal and ichthyotic skin. Twenty students and employees, (12 men and 8 womenaged 25-69 years) served as controls. Patients with ichthyoses were recruited from the outpatient clinic (13 men aged 12-71 years). LÄS MER
2. Dermal absorption of chemicals and toxicity - the role of filaggrin genetics
Sammanfattning : .... LÄS MER
3. Genetic studies of skin barrier defects with focus on atopic dermatitis
Sammanfattning : Atopic dermatitis (AD) is a common, complex inflammatory skin disorder where a defect skin barrier is central in the pathogenesis. Mutations in the filaggrin gene cause ichthyosis vulgaris (IV). IV is one of several keratinization disorders named ichthyoses where mutations in skin barrier genes are a common underlying genetic factor. LÄS MER
4. Genetic studies of candidate genes in eczema
Sammanfattning : Eczema is a common inflammatory skin disorder characterised by itching and relapsing eczematous lesions. It usually presents in early childhood and affects about 10-20% of all children. The background is multifactorial, with both environmental risk factors and hereditary factors contributing to the development of the disease. LÄS MER
5. Aspects of eczema in childhood
Sammanfattning : Eczema (atopic dermatitis) is a common itchy inflammatory skin disease that often starts in childhood. Having eczema is troublesome and has been shown to reduce quality of life. Eczema is associated with an increased risk for other allergy-related diseases such as asthma and rhinitis. LÄS MER