Sökning: "Ficoll"

Visar resultat 1 - 5 av 12 avhandlingar innehållade ordet Ficoll.

  1. 1. Dynamics of the glomerular filtration barrier - Physiological and pathophysiological aspects

    Författare :Josefin Axelsson; Njurmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glomerular filtration barrier; Glomerular permeability; Microalbuminuria; Albumin; Ficoll; Sieving Coefficient; Rats;

    Sammanfattning : The dynamic properties of the glomerular filtration barrier (GFB) are of fundamental importance for the understanding of the physiology and pathophysiology of microalbuminuria and proteinuric diseases. In the studies of this doctoral thesis the properties of the rat glomerular filtration barrier were investigated under resting conditions and following a number of challenges using highly sensitive gel filtration chromatography (HPSEC) detection of FITC-Ficoll in serum and urine. LÄS MER

  2. 2. Nephrotic syndrome causes selective damage to the glomerular charge or size barriers. Physiological mechanisms based onexperimental studies in the rat

    Författare :Maria Ohlson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Bikunin · capillary permeability · charge · Ficoll · glycocalyx · hyaluronan · isolated perfused kidney · kidney glomerulus · serum albumin;

    Sammanfattning : Nephrotic syndrome causes selective damage to the glomerular charge or size barriers. Physiological mechanisms based on experimental studies in the rat. Department of Physiology, Institute for Physiology and Pharmacology, Göteborg University, Box 432, SE-405 30 Gothenburg, Sweden. LÄS MER

  3. 3. Physiological aspects of the glomerular filtration barrier

    Författare :Kristinn Sverrisson; Njurmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Proteinuria is associated with progression of kidney disease and is an independent risk factor for cardiovascular morbidity and mortality. The pathophysiological alterations resulting in proteinuria are obscure, although proteinuria is often associated with pathological changes in the glomerular filtration barrier (GFB). LÄS MER

  4. 4. Folding and interaction studies of subunits in protein complexes

    Författare :Ximena Aguilar; Stefan Björklund; Alexis Verger; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Macromolecular crowding; cpn10; Mediator; Med25; Dreb2a; VP16; conformational changes; NMR; ITC.; biokemi; Biochemistry; molekylärbiologi; Molecular Biology;

    Sammanfattning : Proteins function as worker molecules in the cell and their natural environment is crowded. How they fold in a cell-like environment and how they recognize their interacting partners in such conditions, are questions that underlie the work of this thesis. LÄS MER

  5. 5. Analysis of Transvascular Transport Phenomena in the glomerular and peritoneal microcirculation

    Författare :CARL ÖBERG; Njurmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Peritoneal dialysis; glomerular filtration barrier; pore model; automated peritoneal dialysis APD ; three-pore model;

    Sammanfattning : The current work is devoted entirely to the study of passive transport phenomena, or more specifically, the more simple diffusion, electric migration and filtration of solute matter and water over glomerular and peritoneal capillary walls. The driving forces behind such trans-capillary transport phenomena have long been assumed to be simple gradients of concentration, hydrostatic pressure and electric potential. LÄS MER