Sökning: "Fibrinolysis"

Visar resultat 21 - 25 av 101 avhandlingar innehållade ordet Fibrinolysis.

  1. 21. Impairment of Endothelial Thromboprotective Function by Haemodynamic and Inflammatory Stress - Implications for hypertensive disease

    Författare :Erik Ulfhammer; Göteborgs universitet; []
    Nyckelord :tissue-type plasminogen activator; endothelium; fibrinolysis; hypertension; shear stress; strain; antihypertensive agents; inflammation; TNF-alpha; NF-kappaB; MAPK;

    Sammanfattning : The physiologically most important activator of intravascular fibrinolysis is tissue-type plasminogen activator (t-PA). The endothelium synthesizes and stores t-PA and regulated release of the enzyme is an important local protective response to prevent thrombus extension. LÄS MER

  3. 22. Genetic association studies in stroke

    Författare :Claes Ladenvall; Göteborgs universitet; []
    Nyckelord :stroke; ischemic stroke subtypes; subarachnoid hemorrhage; genetics; polymorphism; fibrinolysis; tPA; PAI-1; TAFI; CRP; Factor XIII;

    Sammanfattning : Stroke is the third most common cause of death and the most common cause of disability in adults in developed countries. It is a complex disease in which genetic and environmental factors make about equal contributions. LÄS MER

  4. 23. Plasminogen Activator Inhibitor 1 in Platelets - Studies of Synthesis, Activity, and Glycosylation Patterns

    Författare :Helén Brogren; Göteborgs universitet; []
    Nyckelord :PAI-1; platelets; plasma; fibrinolysis; synthesis; polymorphism; glycosylation; activity; platelet mRNA;

    Sammanfattning : Plasminogen activator inhibitor 1 (PAI-1) is the main physiological inhibitor of tissue-type plasminogen activator. Thus PAI-1 plays an important role in decreasing the fibrinolytic activity in human blood. PAI-1 is present in high concentrations in platelets and also in low concentrations in plasma, but the source of plasma PAI-1 is not known. LÄS MER

  5. 24. Adipocyte-derived hormones and cardiovascular disease

    Författare :Maria Eriksson; Stefan Söderberg; Tommy Olsson; Lena Jonasson; Umeå universitet; []
    Nyckelord :leptin; adiponectin; fibrinolysis; vWF; myocardial infarction; sex differences; physical activity; risk factors;

    Sammanfattning : Obesity is increasing globally and related to major changes in lifestyle. This increase is associated with an increased risk of cardiovascular disease (CVD). Knowledge about adipose tissue as a metabolic-endocrine organ has increased during the last few decades. LÄS MER

  7. 25. Regulation of vascular endothelial t-PA expression in inflammation: Potential target for pharmacological modulation

    Författare :Pia Larsson; Göteborgs universitet; []
    Nyckelord :Vascular biology; Fibrinolysis; Inflammation; Histone acetylation;

    Sammanfattning : The endogenous fibrinolytic system is important for preventing occluding thrombosis and subsequent tissue infarction. The main activator of the fibrinolytic system in the vascular compartment is tissue-type plasminogen activator (t-PA). LÄS MER