Sökning: "Fibrinolysis"

Visar resultat 11 - 15 av 101 avhandlingar innehållade ordet Fibrinolysis.

1. 11. Circulating biomarkers in patients with abdominal aortic aneurysm

   Författare :Despina Flondell-Sité; Vaskulära sjukdomar - kliniska studier; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; matrix metalloproteinases; biomarkers; risk factors; fibrinolysis; coagulation; inflammation; Abdominal aortic aneurysm; statin; interleukin 6.; APC-PCI complex; serpine-1; endothelin-1;

   Sammanfattning : Abdominal aortic aneurysm (AAA) develops in 3-6% of the population over 65 years and affects mainly men. AAA has a complex etiology involving inflammation, proteolysis, fibrinolysis and coagulation. LÄS MER

3. 12. Early assessment of efficacy and safety of novel anticoagulants as exemplified by direct thrombin inhibitors. Non-clinical pharmacodynamic studies in vitro and in vivo

   Författare :Margareta Elg; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; animals; antidote; bleeding; inhibition constant; inogatran; association rate constant; melagatran; thrombin inhibitor; thrombosis; fibrinolysis;

   Sammanfattning : The drawbacks of today's anticoagulants are parenteral use (heparins), a narrow interval between efficacy and bleeding, and the high variability of effect with a consequent need for frequent monitoring (coumarins). The aim of the current studies was to evaluate properties important for efficacy and safety of novel anticoagulants, as exemplified by direct thrombin inhibitors, with non-clinical methods. LÄS MER

4. 13. Diabetes Mellitus and Cardiovascular Risk : epidemiology, etiology and intervention

   Författare :Aslak Rautio; Kurt Boman; Anna Norhammar; Umeå universitet; []
   Nyckelord :Diabetes; Cardiovascular risk; epidemiology; myocardial infarction; stroke; fibrinolysis; insulin treatment; Diabetes; kardiovaskulär risk; epidemilogi; hjärtinfarkt; stroke; fibrinolys; insulinbehandling; cardiovascular disease; hjärt- och kärlforskning;

   Sammanfattning : Background: The Framingham Study from 1988 showed a heavy impact of diabetes mellitus (DM) on the risk and prognosis of cardiovascular disease (CVD). Several other studies have confirmed that DM is an independent risk factor for coronary heart disease (CHD) and that patients with DM have a poor prognosis. LÄS MER

5. 14. Metabolic Aspects in the Polycystic Ovary Syndrome

   Författare :Åsa Maria Lindholm; Inger Sundström Porormaa; Mari Bixo; Mats Eliasson; Jan Brynhildsen; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PCOS; prevalence; fibrinolysis; inflammatory markers; over weight; Obstetrics and gynaecology; Obstetrik och gynekologi; Obstetrik och gynekologi; Obstetrics and Gynaecology;

   Sammanfattning : Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders among women of childbearing age and is associated with a number of metabolic disturbances. It has been hypothesised these women carry an increased risk of developing cardiovascular diseases (CVD) with advancing age. LÄS MER

7. 15. Risk factors in ischemic stroke

   Författare :Katarina Jood; Göteborgs universitet; []
   Nyckelord :stroke; ischemic stroke subtypes; genetics; polymorphism; fibrinolysis; obesity; stress;

   Sammanfattning : Ischemic stroke is a complex disease in which environmental and genetic factors make about equal contributions to the etiology. However, knowledge regarding the molecular basis of the genetic influence and the impact of specific lifestyle factors is limited. LÄS MER