Sökning: "FcepsilonRI"

Hittade 2 avhandlingar innehållade ordet FcepsilonRI.

  1. 1. Why Is It So Hard to Kill a Mast Cell?A Study of Mast Cell Activation and Survival

    Författare :Xiang Zou; Uppsala universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; A1; allergy; apoptosis; Bfl-1; degranulation; FcepsilonRI; IgE; inflammation; mast cells; nerve growth factor; regranulation; TrkA; Genetik; Clinical genetics; Klinisk genetik; Pathology; patologi;

    Sammanfattning : Mast cells have a long life in tissues, where they are involved in inflammatory and hypersensitivity reactions. Activation through cross-linking of the high-affinity IgE-receptor (FcεRI) is a primary stimulus capable of degranulating mast cells, contributing to symptoms of allergy. LÄS MER

  2. 2. The impact of Bcl-2 family members on mast cell survival and apoptosis

    Författare :Maria Ekoff; Karolinska Institutet; Karolinska Institutet; []

    Sammanfattning : Mast cells are long-lived effector cells of the immune system perhaps best known for their involvement in allergic diseases. There are several acute and chronic inflammations where mast cell accumulation, activation and release of mediators are important for the initiation and perpetuation of the inflammation. LÄS MER