Sökning: "FcγRIIa"

Visar resultat 1 - 5 av 11 avhandlingar innehållade ordet FcγRIIa.

  1. 1. Human candidate polymorphisms and malaria susceptibility in sympatric ethnic groups, The Fulani and The Dogon of Mali

    Författare :Bakary Maiga; Ann-Kristin Östlund Farrants; Lars Hviid; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Malaria; Fulani; Dogon; Blood group; SNPs; IL-4; FcγRIIa; antibody level; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : In malaria endemic regions, resistance to malaria constitutes a critical selective pressureon genetic polymorphisms that regulate immune defense and inflammatory pathways.Differences in malaria susceptibility between sympatric ethnic groups have been described inMali. LÄS MER

  3. 2. Single nucleotide polymorphisms related to immune responses in Plasmodium falciparum malaria

    Författare :Amre Nasr; Klavs Berzins; Marita Troye-Blomberg; Gehad ElGhazali; Thor Theander; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; FcγRIIa-R H131; CRP genotypes; GM KM allotypes; IgG; and malaria; Sudan; Immunology; Immunologi; immunologi; Immunology;

    Sammanfattning : The current research is directed towards dissection of host genetic factors involved in host immune response and the malaria disease outcome. A possible association between FcγRIIa polymorphism and anti-malarial antibody (A.M.A) responses were investigated in Sudanese patients in relation to clinical outcome of falciparum malaria. LÄS MER

  4. 3. Genetic studies on Systemic Lupus Erythematosus : A fine mapping and candidate gene approach

    Författare :Veronica Magnusson; Jerry Lanchbury; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular genetics; Systemic Lupus Erythematosus; complex disease; linkage analysis; candidate gene; association studies; Genetik; Genetics; Genetik; medicinsk genetik; Medical Genetics;

    Sammanfattning : Linkage in the 2q37 region was evaluated using microsatellite markers in multi-case families from Sweden, Iceland and Norway. Both the two-point and the multipoint linkage analysis show highly significant LOD scores (Z=4.51 and 6.03, respectively). LÄS MER

  5. 4. Immune Complex Regulated Cytokine Production in Rheumatic and Lymphoproliferative Diseases

    Författare :Linda Mathsson; Johan Rönnelid; Bo Nilsson; Ann Kari Lefvert; Uppsala universitet; []
    Nyckelord :Immunology; Immune complex; Cytokines; Rheumatic diseases; Lymphoproliferative diseases; Immunologi;

    Sammanfattning : Immune complexes (ICs) are produced during normal immune responses and facilitate clearance of foreign antigens. ICs not efficiently cleared from the circulation can cause tissue damage. This might happen if ICs are formed with autoantibodies and autoantigens. LÄS MER

  7. 5. Signal transduction in human phagocytic cells during phagocytosis, oxidative activation and apoptosis

    Författare :Maria Forsberg; Emmanuelle Caron; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Neutrophils and macrophages are professional phagocytic cells that play a crucial role in host defense against invading microorganisms. They bind to, internalize, and subsequently kill microbes with an arsenal of reactive oxygen metabolites and microbicidal agents. LÄS MER