Sökning: "Fatty acid metabolism"

Visar resultat 6 - 10 av 199 avhandlingar innehållade orden Fatty acid metabolism.

1. 6. Cytochrome P450 Enzymes in Bile Acid Biosynthesis and Fatty Acid Metabolism : Studies on Members of the Porcine CYP4A and CYP8B Subfamilies

   Författare :Kerstin Lundell; Kjell Wikvall; Ronnie Hansson; Stefan Alexson; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical biochemistry; cytochrome P450; bile acids; fatty acids; CYP4A; CYP8B; genome; porcine; hyocholic acid; Farmaceutisk biokemi; Pharmaceutical biochemistry; Farmaceutisk biokemi; farmaceutisk biokemi; Pharmaceutical Biochemistry;

   Sammanfattning : The present investigation is devoted to studies on porcine members of the cytochrome P450 4A (CYP4A) and CYP8B1 subfamilies, which are involved in bile acid biosynthesis and fatty acid metabolism. Hyocholic acid is considered to fulfil the requirements for trihydroxy bile acids in the domestic pig (Sus scrofa) in the absence of cholic acid. LÄS MER

3. 7. Dietary Fatty Acids, Body Composition and Ectopic Fat : Results from Overfeeding Studies in Humans

   Författare :Fredrik Rosqvist; Ulf Risérus; Tommy Cederholm; Ian Macdonald; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Linoleic acid; Palmitic acid; SFA; PUFA; Fatty acids; Body composition; Liver fat; Ectopic fat; Adipose tissue; Medicinsk vetenskap; Medical Science;

   Sammanfattning : The aim of this thesis was to investigate the effects of dietary fatty acids on body composition and ectopic fat in humans, with emphasis on the role of the omega-6 polyunsaturated fatty acid (PUFA) linoleic acid (18:2n-6) and the saturated fatty acid (SFA) palmitic acid (16:0). The overall hypothesis was that linoleic acid would be beneficial compared with palmitic acid during overfeeding, as previously indicated in animals. LÄS MER

4. 8. Dietary Fatty Acids and Cardiometabolic Risk : Influence on Lipoproteins, Insulin Resistance and Liver Fat

   Författare :David Iggman; Ulf Risérus; Tommy Cederholm; Åke Nilsson; Uppsala universitet; []
   Nyckelord :Linoleic acid; Palmitic acid; PUFA; SFA; n-6 fatty acids; Medicinsk vetenskap; Medical Science;

   Sammanfattning : The aim of this thesis was to investigate how dietary fatty acids affect the risk for cardiometabolic disease, i.e. cardiovascular disease (CVD), type 2 diabetes and obesity. LÄS MER

5. 9. Fat metabolism : A clinical and experimental study with special reference to newborns

   Författare :Gertrud Angsten; Karl-Anders Dahlström; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; neonates; total parenteral nutrition; plasma and muscle carnitine; carnitine reference intervals; medium-chain triglycerides; Kirurgi; Surgery; Kirurgi; kirurgi; särskilt barnkirurgi; Pediatric Surgery;

   Sammanfattning : Lipid emulsion is an important constituent of total parenteral nutrition (TPN). In the investigations described in this thesis the effects of different lipid emulsions in neonates were studied. LÄS MER

7. 10. Protein Complexity via Non-Native States: Binding, Stability, and Structural Studies of Calbindin D9k and HAMLET (Human alpha-lactalbumin Made LEthal to Tumor cells)

   Författare :Jonas Fast; Biofysikalisk kemi; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; apoptosis; oleic acid; HAMLET; kinetic trap alpha-lactalbumin; calbindin; calcium; Metabolism; Biokemi; metabolism;

   Sammanfattning : Using optical spectroscopy, nuclear magnetic resonance (NMR), and differential scanning Calorimetry (DSC), I have studied two different calcium binding proteins that can form kinetically trapped altered states. Calcium is very important in numerous biological processes such as blood coagulation, signal transduction, muscle contraction and bone formation. LÄS MER