Sökning: "Fate map"

Visar resultat 1 - 5 av 11 avhandlingar innehållade orden Fate map.

  1. 1. Cell fate specification by Ras-mediated cell signalling in C. elegans

    Författare :Teresa Tiensuu; Simon Tuck; Benjamin Podbilewicz; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; cell signalling; Ras; vulva precursor cell; lin-25; sur-2; lin-1; cell fate specification; Mediator; vulva induction; transcriptional regulation; Cell- och molekylärbiologi; Cell and molecular biology; Cell- och molekylärbiologi;

    Sammanfattning : Induction of vulval fates in the C. elegans hermaphrodite is mediated by a conserved RTK/Ras/MAP kinase signalling pathway, in which the core components can be placed into a linear genetic and biochemical pathway. However, the events that occur downstream of this pathway are not yet well understood. LÄS MER

  3. 2. Early fate decisions in hematopoietic stem and progenitor cells. Through the lens of genomic and functional assays

    Författare :Fatemeh Safi; Avdelningen för molekylär hematologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hematopoiesis; HSCs; singel cell sc ; scRNA-seq; scATAC-seq; CD9; Aging;

    Sammanfattning : Hematopoietic stem cells (HSCs) are rare cells on top of the differentiation hierarchy of hematopoiesis. HSCs are unique in their combined capacity to differentiate into all mature blood lineages and self-renew to maintain the HSC pool. LÄS MER

  4. 3. A Comparative Study of Head Development in Mexican Axolotl and Australian Lungfish: Cell Migration, Cell Fate and Morphogenesis

    Författare :Rolf Ericsson; Rolf Ohlsson; Graham Budd; Lennart Olsson; Per Ahlberg; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Developmental biology; Head development; axolotl; lungfish; Utvecklingsbiologi; Developmental biology; Utvecklingsbiologi; Developmental Biology; miljömedicinsk utvecklingsbiologi;

    Sammanfattning : The development of the vertebrate head is a complex process involving interactions between a multitude of cell types and tissues. This thesis describes the development of the cranial neural crest and of the visceral arch muscles in the head of two species. LÄS MER

  5. 4. Characterization of human myeloid progenitors and their differentiation

    Författare :Louise Edvardsson; Avdelningen för hematologi och transfusionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine human and vertebrates ; extracellular fluids; Haematology; Medicin människa och djur ; thrombopoietin receptor; hematopoiesis; transcription factors; growth factor receptors; human myeloid progenitors; Hematologi; extracellulära vätskor;

    Sammanfattning : All hematopoietic cells are derived from the hematopoietic stem cells (HSCs) in a continuous and dynamic process, regulated by a network of transcription factors in different combinations and extrinsic signals from growth factors (GFs) and other factors in the microenvironment. In the initial stages of hematopoiesis HSCs differentiate to progenitor cells with gradually more restricted lineage potential and according to the most accepted model the first restriction in developmental potential results in commitment to either the lymphoid or the myeloid branch, in the latter followed by commitment to the neutrophil/monocyte and erythrocyte/megakaryocyte lineages. LÄS MER

  7. 5. Distribution and regulation of auxin in Arabidopsis root cells

    Författare :Sara Petersson; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : The plant hormone auxin (IAA) coordinates many of the important processes in plant development. For example, IAA is critical for normal embryogenesis, root development, cell elongation, and the tropic responses such as gravitropism and phototropism. LÄS MER