Avancerad sökning

Hittade 2 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. [11C]Carbon Monoxide in Palladium- / Selenium-Promoted Carbonylation Reactions : Synthesis of 11C-Imides, Hydrazides, Amides, Carboxylic Acids, Carboxylic Esters, Carbothioates, Ketones and Carbamoyl Compounds

    Författare :Farhad Karimi; Kalman Szabo; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; Organisk kemi; Organic chemistry; Organisk kemi; organisk kemi; Organic Chemistry;

    Sammanfattning : [11C]Carbon monoxide in low concentrations has been used in palladium- or seleniummediated carbonylation reactions such as the synthesis of 11C-imides, hydrazides, amides, carboxylic acids, esters, carbothioates, ketones and carbamoyl compounds.In these reactions aryl iodides have been used in most cases. LÄS MER

  2. 2. Development of 18F- and 68Ga-Labelled Tracers : Design Perspectives and the Search for Faster Synthesis

    Författare :Elisabeth Blom; Bengt Långström; Oleksiy Itsenko; Irina Velikyan; Farhad Karimi; Frank Rösch; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; PET; nucleophilic 18F-fluorination; perfluoro; F-SPE; molecular design; 68Ga; chelators; DOTA; NOTA; microwave; halogen exchange; harmine; biotin; RGD; VEGF; CRP; Chemistry; Kemi; Organisk kemi; Organic Chemistry;

    Sammanfattning : This thesis deals with the design of 18F- and 68Ga-labelled positron emission tomography (PET) tracers and the development of technologies that enable faster and simpler preparation with high specific radioactivity. Techniques like microwave heating and reducing the concentrations of the precursor were investigated with this perspective. LÄS MER