Sökning: "False positive signals"

Visar resultat 1 - 5 av 12 avhandlingar innehållade orden False positive signals.

  1. 1. Regulation of T-cell proliferation and B-CLL apoptosis by CD6 and FAS/FASL

    Detta är en avhandling från Stockholm : Karolinska Institutet, false

    Författare :Lydia Maria Osorio Fernández; Karolinska Institutet.; Karolinska Institutet.; [1998]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; T-cell activation; CD6; B-CLL; apoptosis; Fas; FasL;

    Sammanfattning : T-cell activation involves the interaction between the T-cell receptor (TCR) and the peptide/MHC complex presented on an antigen-presenting cell. However, this is not sufficient for the full development of T cell responses and co-stimulatory signals from accessory molecules are required. LÄS MER

  2. 2. Triggering and inhibitory molecules affecting target cell recognition by NK cells

    Detta är en avhandling från Stockholm : Karolinska Institutet, false

    Författare :Margarita Salcedo; Karolinska Institutet.; Karolinska Institutet.; [1997]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NK cell; MHC class 1; NKinhibitory receptors; costimulatory molecules ISBN 9 1-628-2643-3;

    Sammanfattning : TRIGGERING AND INHIBITORY MOLECULESAFFECTING TARGET CELL RECOGNITION BY NK CELLS Margarita Salcedo Doctoral dissertation from the Microbiology and Tumor Biology Center KarolinskaInstitute, Stockholm, Sweden NK cells were described originally for their ability to Iyse certain tumor celllines without prior immunization. MHC class I molecules have been shown to delivera negative signal to NK cells. LÄS MER

  3. 3. Isolation and characterization of genes within the region for multiple endocrine neoplasia type 1 on chromosome 11q13

    Detta är en avhandling från Stockholm : Karolinska Institutet, false

    Författare :Jacob Lagercrantz; Karolinska Institutet.; Karolinska Institutet.; [1996]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Multiple Endocrine Neoplasia type 1 MEN1 ; Chromosome 11q13; Phospholipase C Beta 3 gene PLCB3 ; Phospholipase C Beta 3 Neighbouring Gene PNG ; Vascular Endothelial Growth Factor VEGF ; VEGF Related Factor gene VRF .;

    Sammanfattning : This thesis summarizes the investigations of three genes isolated from the locus for multiple endocrine neoplasia type 1 (MEN1) within the chromosomal region 11q13. As a common strategy for all three genes, the cDNA was sequenced, the genomic structure characterized, and the expression pattern analyzed by Northern blotting on human tissues and by in situ RNA hybridization on slides from rodent embryos. LÄS MER

  4. 4. Track circuits’ robustness Modeling, measurement and simulation

    Detta är en avhandling från Stockholm : Karolinska Institutet, false

    Författare :Emilio Rodriguez; Luleå tekniska universitet.; [2014]
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Track circuit; Relay; False positive signals; Signalling in railway; Modelling; Simulation; Testing; Robustness; Interoperability; Reliability; Railway Infrastructure; Technology - Electrical engineering; electronics and photonics; Information technology - Telecommunication; Information technology - Computer engineering; Technology - Engineering physics; Information technology - Systems engineering; Teknikvetenskap - Elektroteknik; elektronik och fotonik; Informationsteknik - Telekommunikation; Informationsteknik - Datorteknik; Teknikvetenskap - Teknisk fysik; Informationsteknik - Systemteknik; Drift och underhållsteknik; Operation and Maintenance;

    Sammanfattning : In countries with rough weather conditions, frequent delays cause railway companies to waste time and money. Many of these delays are related to the train detection systems, as the old DC track circuits are still used in some countries, including Sweden, our case study. LÄS MER

  5. 5. Aβ Conformation Dependent Antibodies and Alzheimer's Disease

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Dag Sehlin; Uppsala universitet.; [2010]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alzheimer s disease; amyloid-beta; protofibrils; conformation; monoclonal antibody; ELISA; MEDICINE; MEDICIN; Geriatrics; Geriatrik;

    Sammanfattning : Soluble intermediates of the amyloid-β (Aβ) aggregation process are suggested to play a central role in the pathogenesis of Alzheimer’s disease (AD) by causing synaptic dysfunction and neuronal loss. In this thesis, soluble Aβ aggregates have been studied with a particular focus on the Aβ protofibril, which has served as the antigen for developing conformation dependent monoclonal antibodies. LÄS MER