Sökning: "FGF-2"

Visar resultat 21 - 25 av 39 avhandlingar innehållade ordet FGF-2.

  1. 21. The impact of vascular structure and function on tumor growth, retinopathy, and antiangiogenic therapy

    Författare :Eva-Maria Hedlund; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Tumors produce multiple angiogenic factors to stimulate neovascularization that is essential for tumor growth, invasion and metastasis. Despite the known angiogenic functions of each individual factor, the interplay between these angiogenic factors in the tumor local environment and in modulation of the host functions remain poorly understood. LÄS MER

  3. 22. Angiogenesis in obesity and cancer

    Författare :Ebba Bråkenhielm; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Adiponectin; endothelial cells; Leptin; Resveratrol; TNP-470;

    Sammanfattning : Angiogenesis is the process of blood vessel growth from pre-existing vasculatures. In the adult, it is involved in certain physiological processes, such as in organ and tissue regeneration, wound healing, and in female reproductive cycles. LÄS MER

  4. 23. Mechanisms of Tissue Vascularization

    Författare :Witold Kilarski; Pär Gerwins; Lena Claesson-Welsh; Andreas Bikfalvi; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pathology; vascularization; angiogenesis; granulation tissue; myofibroblast; wound healing; Patologi; Pathology; Patologi;

    Sammanfattning : Tissue neovascularization in postnatal life occurs during post-traumatic tissue healing, neoplastic growth and in the endometrium during the reproductive cycle of females. Although embryonic angiogenesis has been intensively studied, far less is known about tissue revascularization and vessel remodeling in adults due to methodological difficulties. LÄS MER

  5. 24. Application of a New Logic to Old Drugs: Angiogenesis Inhibition in Neuroblastoma

    Författare :Åsa Svensson; Rolf Christofferson; Per Kogner; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cell biology; angiogenesis; neuroblastoma; CHS 828; digoxin; combination treatment; Cellbiologi; Cell biology; Cellbiologi; Medical Cell Biology; medicinsk cellbiologi;

    Sammanfattning : Neuroblastoma is one of the most common solid cancers of early childhood. In Sweden, approximately 10-15 cases occur annually. The overall five-year neuroblastoma survival in Europe is approximately 45%. Since cancer treatment involves drugs with risks of side effects in the growing child, there is a need for more effective and less toxic drugs. LÄS MER

  7. 25. Effect of Hyaluronan-activation of CD44 on Cell Signaling and Tumorigenesis

    Författare :Lingli Li; Paraskevi Heldin; Raija H. Tammi; Uppsala universitet; []
    Nyckelord :Biomedicine; Hyaluronan; CD44; growth factors; chemokines; tumorigenesis; wound healing; cell signaling; Biomedicin;

    Sammanfattning : Hyaluronan (HA), a structural component in the extracellular matrix (ECM), has been recognized as a signaling molecule. It is important during various biological activities such as embryogenesis, angiogenesis, wound healing and tumor progression. LÄS MER