Sökning: "FGF receptor"

Visar resultat 21 - 25 av 41 avhandlingar innehållade orden FGF receptor.

  1. 21. Growth factors in spermatogenesis

    Författare :Aida Wahlgren; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Testis; seminiferous tubules; proliferation; growth factors; sex steroids;

    Sammanfattning : The aim of this study was to increase the knowledge of die effects of locally produced growth factors and hormones on germ cell proliferation in rat testis in vitro. Since impaired sperm production and function accounts for half the cases of infertility, it is important to understand the physiological actions in germ cell development. LÄS MER

  3. 22. The role of Klotho in mineral metabolism and inflammation

    Författare :Risul Amin; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Accumulated data suggest that a disrupted FGF23-Klotho axis is a major contributor to the development of chronic kidney disease (CKD). This axis might have a broader role in the regulation of inflammation, yet the underlying mechanisms remain largely elusive. LÄS MER

  4. 23. Targeting stromal components in the tumor microenvironment for cancer therapy

    Författare :Jieyu Wu; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : In the tumor microenvironment (TME), different cell components crosstalk with each other through various growth factors, cytokines, chemokines, and enzymes. They offered crucial survival signals for tumor cell proliferation and metastasis. LÄS MER

  5. 24. Protein tyrosine kinases in insulin producing cells : Expression and putative importance for beta-cell function

    Författare :Charlotte Öberg-Welsh; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; Protein tyrosine kinase; insulin producing cells; fetal development; VEGF; Src-family; Bsk; Cellbiologi; Cell biology; Cellbiologi; medicinsk cellbiologi; Medical Cell Biology;

    Sammanfattning : Protein tyrosine kinases are of importance for cell replication and differentiation in manysystems. The mechanisms controlling the replication and differentiation of insulin producingcells are unknown. LÄS MER

  7. 25. Effect of Hyaluronan-activation of CD44 on Cell Signaling and Tumorigenesis

    Författare :Lingli Li; Paraskevi Heldin; Raija H. Tammi; Uppsala universitet; []
    Nyckelord :Biomedicine; Hyaluronan; CD44; growth factors; chemokines; tumorigenesis; wound healing; cell signaling; Biomedicin;

    Sammanfattning : Hyaluronan (HA), a structural component in the extracellular matrix (ECM), has been recognized as a signaling molecule. It is important during various biological activities such as embryogenesis, angiogenesis, wound healing and tumor progression. LÄS MER