Sökning: "FGF receptor"

Visar resultat 16 - 20 av 41 avhandlingar innehållade orden FGF receptor.

  1. 16. Fibroblast growth factor-induced signal transduction

    Författare :Peter Klint; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; Biokemi; Biochemistry; Biokemi; molekylär cellbiologi; Molecular Cellbiology;

    Sammanfattning : Fibroblast growth factors (FGFs) evoke cellular responses by binding to FGF receptors (FGFRs). FGFRs are cell surface expressed membrane-spanning receptors with intrinsic stimulatable tyrosine kinase activity. This thesis describes the cell proliferation or differentiation. LÄS MER

  3. 17. Regulation of Angiogenesis

    Författare :Helena Larsson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; angiogenesis; anti-angiogenesis; endostatin; latent antithrombin; prelatent antithrombin; Crk; Genetik; Clinical genetics; Klinisk genetik; Pathology; patologi;

    Sammanfattning : Angiogenesis is the formation of new blood vessels from pre-existing ones. New blood vessel formation is fundamental in processes such as reproduction, embryonic development and wound healing. Growth of neoplasms is accompanied by increased angiogenesis. This thesis describes cellular and molecular mechanisms of importance for angiogenesis. LÄS MER

  4. 18. Investigation of hepatocyte signaling pathways in chronic kidney disease : clinical and experimental studies

    Författare :Meng Li; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Chronic kidney disease (CKD) is defined as a loss of renal function from any cause and lasting for more than three months. The CKD phenotype is similar across multiple etiologies, suggesting that renal damage itself is a dominant factor. LÄS MER

  5. 19. The role of VEGF family in angiogenesis, tumor growth and metastasis

    Författare :Xiaojuan Yang; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Tumor growth is dependent on angiogenesis, and cells in tumor tissues produce various angiogenic factors to induce neovascularization. Among tumor-derived angiogenic factors, members of the vascular endothelial growth factor (VEGF) family are most frequently and highly expressed in various solid tumors. LÄS MER

  7. 20. Ephrins off the beaten path

    Författare :Johan Holmberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The Orchestration of cell-cell interactions is crucial to the developing embryo and the adult organism. Intercellular communication is to a large extent controlled by signalling events downstream of receptor tyrosine kinases (RTKs). Ligands for RTKs are often soluble and confer long distance information to the receptor expressing cell. LÄS MER