Sökning: "FFPE"

Visar resultat 1 - 5 av 18 avhandlingar innehållade ordet FFPE.

  1. 1. The use of formalin fixed paraffin embedded tissue and global gene expression profiling for increased understanding of squamous cell carcinoma of the tongue

    Författare :Rentoft Matilda; Karin Nylander; Michael Prystowsky; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; SCCHN; tongue; microarray; DASL; FFPE; archival; mRNA; miRNA; patologi; Pathology;

    Sammanfattning : Head and neck cancer is the 6th most common malignancy worldwide, with tumours of the tongue being one of the most prevalent sites. Despite advances in surgery and radiotherapy, the five-year survival has not changed during the last decades and remains at approximately 50%. LÄS MER

  3. 2. Essays on spatial point processes and bioinformatics

    Författare :Jessica Fahlén; Patrik Rydén; Xavier de Luna; Yudi Pawitan; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Coverage process; vacancy; microarray; pre-processing; sensitivity; bias; dye-normalization; FFPE; storage time effects; Statistics; Statistik; Statistics; statistik;

    Sammanfattning : This thesis consists of two separate parts. The first part consists of one paper and considers problems concerning spatial point processes and the second part includes three papers in the field of bioinformatics. LÄS MER

  4. 3. The Spatial Context – through the lens of method development

    Författare :Linda Kvastad; Joakim Lundeberg; Lars Feuk; KTH; []
    Nyckelord :RNA; RNA-sequencing; transcriptomics; spatial transcriptomics; single cells; pediatric brain tumors; Spatial RIN; Bioteknologi; Biotechnology;

    Sammanfattning : In the present moment of time, we find ourselves in a period where the advancement of genomic tools is progressing at a fast pace. Of particular interest for this thesis is the study of gene activity. LÄS MER

  5. 4. Usefulness of archival biobank samples for genetic epidemiologic studies

    Författare :Malin Sjöholm; Malmö Klinisk mikrobiologi; []
    Nyckelord :formailn-fixed paraffin-embedded tissue; biobank; serum; dried blood spots; plasma; archival samples;

    Sammanfattning : Sweden has a long history of maintaining population-based registries and biobanks. This has resulted in large sample collections with long follow-up and large numbers of prospectively occurring disease endpoints providing an extensive resource for genetic research. LÄS MER

  7. 5. Regulation of molecular processes in diffuse large B-cell lymphoma

    Författare :Therese Högfeldt; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The molecular understanding of diseases has advanced rapidly due to the use of gene expression profiling. However, these methods have been hampered by the limitation to use frozen tissue specimens. Formalin fixation and paraffin embedding (FFPE) is a standard procedure for long time storage of tissues. LÄS MER