Sökning: "FCCS"

Hittade 4 avhandlingar innehållade ordet FCCS.

  1. 1. Fluorescence fluctuation studies of biomolecular interactions in solutions, biomembranes and live cells

    Författare :Volodymyr Chmyrov; Jerker Widengren; Antoine Delon; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; FCS; FCCS; Isomerization; TRAST; NMR; FRET; biomombrane; fluidity; Biological Physics; Biologisk fysik;

    Sammanfattning : Fluorescence spectroscopy and imaging have a very broad spectrum of applicationswithin the life sciences, in particular for detection and characterization ofbiomolecular dynamics and interactions in different environments. This thesis comprisesprojects that strive to further expand the information content extracted fromthe detected fluorescence, leading to sensitive readout parameters for studies ofbiomolecular dynamics and interactions. LÄS MER

  3. 2. Interactions between the opioid and serotonin systems in chronic pain : quantitative live cell study by fluorescence cross-correlation spectroscopy (FCCS)

    Författare :Vlad Radoi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Chronic pain is a major health issue worldwide. It enacts considerable suffering on the affected individuals and significantly increases the societal burden, as it is the most common reason why individuals seek sick leave and ask for medical help. LÄS MER

  4. 3. Fluorescence Studies of Membranes -- Proteins and Lipids, their Dynamics and Interactions

    Författare :Johan Strömqvist; Jerker Widengren; Thorsten Wohland; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Fluorescence correlation spectroscopy; cytokinesis; collision theory; protein-protein interactions; lipid dynamics; single-molecule experiment; Biological physics; Biologisk fysik;

    Sammanfattning : In this thesis, fluorescence spectroscopy was utilized to probe protein and lipid dynamics and interactions in their native, or close to native, environments. Thereby insight could be gained into the fundamentals of bacterial cell division and the innateimmune system. A particular focus has been devoted to fluorescence fluctuations. LÄS MER

  5. 4. Super resolution fluorescence imaging : analyses, simulations and applications

    Författare :Jan Bergstrand; Jerker Widengren; Eilon Sherman; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Physics; Fysik;

    Sammanfattning : Fluorescence methods offer extraordinary sensitivity and specificity, and are extensively used in the life sciences. In recent years, super resolution fluorescence imaging techniques have developed strongly, uniquely combining ~10 nm sub diffraction resolution and specific labeling with high efficiency. LÄS MER