Sökning: "FARMACI Farmaceutisk kemi"

Visar resultat 16 - 17 av 17 avhandlingar innehållade orden FARMACI Farmaceutisk kemi.

1. 16. Spray-Dried Powders for Inhalation : Particle Formation and Formulation Concepts

   Författare :Jessica Elversson; Göran Alderborn; Anna Millqvist-Fureby; Lars Hovgaard; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutics; Spray drying; Particle formation; Density; Protein formulation; Encapsulation; Coating; Competitive adsorption; Polymer; ESCA; AFM; FTIR; Galenisk farmaci; Pharmaceutics; Galenisk farmaci;

   Sammanfattning : Spray drying is a method with a high potential in the preparation of protein particles suitable for pulmonary delivery. However, surface induced denaturation of bio-molecules during atomization and subsequent drying can be substantial and it is therefore important to develop new formulation concept for concurrent encapsulation and stabilization of proteins during spray drying. LÄS MER

3. 17. Amphiphilic Peptide Interactions with Complex Biological Membranes : Effect of peptide properties on antimicrobial and anti-inflammatory effects

   Författare :Shalini Singh; Martin Malmsten; Per Hansson; Debora Berti; Uppsala universitet; []
   Nyckelord :LPS; Antimicrobial; Peptide; Inflammation; Infections; Liposome; Binding; PEG; Farmaceutisk fysikalisk kemi; Pharmaceutical Physical Chemistry;

   Sammanfattning : With increasing problem of resistance development in bacteria against conventional antibiotics, as well as problems associated with diseases either triggered or enhanced by infection, there is an urgent need to identify new types of effective therapeutics for the treatment of infectious diseases and its consequences. Antimicrobial and anti-inflammatory peptides have attracted considerable interest as potential new antibiotics in this context. LÄS MER