Sökning: "FAE"

Visar resultat 1 - 5 av 12 avhandlingar innehållade ordet FAE.

  1. 1. Particle Transcytosis Across the Human Intestinal Epithelium : Model Development and Target Identification for Improved Drug Delivery

    Författare :Elisabet Gullberg; Per Artursson; Barry Hirst; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutics; M-cell; FAE; Peyer´s patches; oral vaccination; uptake; endocytosis; Galenisk farmaci; Pharmaceutics; Galenisk farmaci;

    Sammanfattning : The use of nano- and micro-particulate carriers as delivery systems for oral vaccines has been under investigation for several decades. Surprisingly little is known of their uptake in the human intestine, despite the fact that substantial improvement is required to achieve adequate immune responses in man after oral administration. LÄS MER

  3. 2. Land och fæ : strukturellt-rättsfilologiska studier i fornnordiskt lagspråk över beteckningar för egendom i allmänhet med underkategorier

    Författare :Bo Ruthström; tolkning i offentlig sektor och översättning danska och isländska Avdelningen för svenska; []
    Nyckelord :HUMANIORA; HUMANITIES; Språkvetenskap; Philology; pre-medieval; regional law; medieval law; linguistic geography; onomasiology; terminology; property in general; movable and immovable property; structural shift; Old Nordic; Proto-Nordic; lauss eyrir; Roman law; Christian church; legal history; Harald Bluetooth; Hákon Aðalsteinsfóstri; Harald Finehair; Scandinavian languages and literature; Nordiska språk språk och litteratur ;

    Sammanfattning : This study investigates the stock of words for PROPERTY IN GENERAL with the subcategories MOVABLE and IMMOVABLE PROPERTY in the regional medieval Scandinavian laws and makes a linguistic-geographical analysis of these words with the aim of establishing a relative term chronology. A crude analysis shows that fé/fæ for PROPERTY IN GENERAL and land for IMMOVABLE PROPERTY were the oldest terms. LÄS MER

  4. 3. Effects of Microparticulate Drug Delivery Systems : Tissue Responses and Transcellular Transport

    Författare :Eva Ragnarsson; Per Artursson; Lucia Lazorova; David Brayden; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutics; microparticles; vaccine; pDNA vaccine; cationic polymer; gene expression analysis DNA array ; Caco-2; follicle-associated epithelium FAE ; M cell; transcytosis; Yersinia pseudotuberculosis; Galenisk farmaci; Pharmaceutics; Galenisk farmaci;

    Sammanfattning : Over the past decade, the development of macromolecular drugs based on peptides, proteins and nucleic acids has increased the interest in microparticulate drug delivery, i.e., the delivery of drug systems in the nanometer and micrometer ranges. LÄS MER

  5. 4. Barrier function of the Follicle-Associated Epithelium in Stress and Crohn's disease

    Författare :Åsa Keita; Johan D. Söderholm; Ann-Charlott Ericson; Björn Weström; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Corticotropin-releasing hormone; Crohn’s disease; 51Cr- EDTA; Escherichia coli; follicle-associated epithelium; horseradish peroxidase; human; ileum; inflammatory bowel disease; intestinal mucosa; mast cell; M cell; permeability; Peyer’s patches; rat; Ussing chamber; vasoactive intestinal peptide; villus epithelium; Surgery; Kirurgi;

    Sammanfattning : Crohns sjukdom är en kronisk inflammatorisk tarmsjukdom av okänd orsak. Det tidigaste tecknet på Crohns sjukdom är mikroskopiska sår i det s.k. follikelassocierade epitelet (FAE) som täcker ansamlingar av immunceller i tarmen. LÄS MER

  7. 5. Bacterial epithelial interaction in intestinal inflammation

    Författare :Lina Yakymenko Alkaissi; Åsa Keita; Johan D Söderholm; Maria Magnusson; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : The intestine is constantly exposed to bacteria, invading viruses and ingested food. The intestinal barrier serves as a gate preventing passage of harmful components, and at the same time maintaining absorption of nutrients and water. LÄS MER