Sökning: "F2-isoprostanes"
Visar resultat 1 - 5 av 7 avhandlingar innehållade ordet F2-isoprostanes.
1. Measurement and Evaluation of Antioxidant Status and Relation to Oxidative Stress in Humans
Sammanfattning : Numerous diseases are associated with reduced antioxidant defence and oxidative stress. The antioxidant defence includes dietary and endogenous antioxidants and involves complex interactions between them. LÄS MER
2. Homocysteine and Coronary Artery Disease With special Reference to Biochemical Effects Of Vitamin Therapy
Sammanfattning : An elevated plasma level of homocysteine has been suggested as a risk factor for cardiovascular disease. The objectives of this thesis were to study the influence of renal function on homocysteine levels in patients with coronary artery disease and to explore the association of elevated plasma levels of homocysteine to oxidative stress, inflammation, and endothelial dysfunction. LÄS MER
3. Oxidative Stress, Angiogenesis and Inflammation in Normal Pregnancy and Postpartum
Sammanfattning : The aims were to investigate oxidative stress (I), angiogenesis (II) and inflammation (III-IV) in healthy women during pregnancy and postpartum. Oxidative stress was estimated by measurement of 8-iso-PGF2α and the antioxidants α- and γ-tocopherol. LÄS MER
4. Lipid peroxidation in vivo : Evaluation and application of methods for measurement
Sammanfattning : Lipid peroxidation is thought to be an important factor in the pathophysiology of a number of diseases and in the process of ageing, but its measurement in vivo has been difficult. The aim of this thesis was to evaluate methods for measurement of lipid peroxidation in vivo that are suitable for clinical investigations, and to apply these methods in animal and human studies investigating basal conditions and situations associated with increased lipid peroxidation. LÄS MER
5. Lung mechanics and airway inflammation in murine models of asthma
Sammanfattning : Allergic asthma is an inflammatory disease of the airways and is characterized by eosinophilic inflammation and increased airway reactivity. In the studies presented in this thesis, lung mechanics and measurements of airway reactivity were assessed in anaesthetized tracheostomized mice by using an animal ventilator (flexiVent®). LÄS MER